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PRLR
This is a receptor for the anterior pituitary hormone prolactin.
Protein class
Disease related genes, FDA approved drug targets, Human disease related genes
Predicted location
Intracellular, Membrane (different isoforms)
Single cell type specificity
Cell type enhanced (Endometrial stromal cells, Granulosa cells, Breast glandular cells, Proximal tubular cells, Syncytiotrophoblasts)
Immune cell specificity
Not detected in immune cells
Cell line specificity
Cell line enriched (T-47d)
Interaction
Homodimer upon hormone binding. Interacts with SMARCA1. Interacts with GH1. Interacts with CSH. Interacts with NEK3 and VAV2 and this interaction is prolactin-dependent.
Molecular function
Receptor
More Types Infomation
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- Species Reactivity: Human
- Type: Mouse Fab
- Application: ELISA, Neut, WB
-
- Species Reactivity: Human
- Type: Mouse scFv
- Application: WB, ELISA, FuncS
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- Species Reactivity: Human
- Type: Mouse scFv
- Application: ELISA, Neut, WB
-
- Species Reactivity: Human
- Type: Mouse IgG
- Application: ELISA
-
- Species Reactivity: Human
- Type: Mouse Fab
- Application: WB, ELISA, FuncS
-
- Derivation: Mouse
- Species Reactivity: Human
- Type: Mouse IgG1, κ
- Application: FC, ICC, IF, IHC
-
- Species Reactivity: Human
- Type: Mouse scFv
- Application: ELISA
-
- Species Reactivity: Human
- Type: Mouse Fab
- Application: ELISA
- Recombinant Mouse Anti-PRLR Antibody (CBL154) (NEUT-1881CQ)
-
- Species Reactivity: Human
- Type: IgG1
- Application: Neut, WB
-
- Species Reactivity: Human
- Type: Mouse IgG
- Application: ELISA, Neut, WB
-
- Species Reactivity: Human
- Type: Mouse IgG
- Application: WB, ELISA, FuncS
- Recombinant Mouse Anti-PRLR Antibody (CBL359) (NEUT-1882CQ)
-
- Species Reactivity: Human
- Type: IgG1
- Application: Neut, WB
- Recombinant Mouse Anti-PRLR Antibody (6G8) (NEUT-1883CQ)
-
- Species Reactivity: Human
- Type: IgG1
- Application: Neut, WB
- Recombinant Mouse Anti-PRLR Antibody (T6) (NEUT-1884CQ)
-
- Species Reactivity: Human, Mouse, Rat, Sheep
- Type: IgG2a
- Application: BL, FC, ICC/IF, IHC, IP, WB
-
- Derivation: Phage display library screening
- Species Reactivity: Mouse, Rat, Human
- Type: IgG
- Application: WB, IHC-P, ICC/IF
-
- Species Reactivity: Human
- Application: ELISA, WB
- Recombinant Mouse Anti-PRLR Antibody (U5) (NEUT-1885CQ)
-
- Species Reactivity: Human, Mouse, Pig, Rat, Horse, Primate, Rabbit, Sheep
- Type: IgG1
- Application: BL, FC, ICC/IF, IHC, IHC-Fr, IHC-P, IP, WB
- Mouse Anti-PRLR Antibody (clone sAB A8), mRNA (PABL-682-mRNA)
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- Species Reactivity: Human
- Human Anti-PRLR Recombinant Antibody (MOB-219YJL) (MOB-219YJL)
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- Species Reactivity: Human, Mouse
- Type: Human IgG1
- Application: ELISA, FC, Inhib
- Human Anti-PRLR Recombinant Antibody; scFv Fragment (MOB-219YJL-S(P)) (MOB-219YJL-S(P))
-
- Species Reactivity: Human, Mouse
- Type: Human scFv
- Application: ELISA, FC, Inhib
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For Research Use Only. Not For Clinical Use.