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PTGES2

The protein encoded by this gene is a membrane-associated prostaglandin E synthase, which catalyzes the conversion of prostaglandin H2 to prostaglandin E2. This protein also has been shown to activate the transcription regulated by a gamma-interferon-activated transcription element (GATE). Multiple transcript variants have been found for this gene. [provided by RefSeq, Jun 2009]
Protein class

Enzymes, Human disease related genes, Metabolic proteins

Predicted location

Intracellular

Single cell type specificity

Cell type enriched (Cardiomyocytes)

Immune cell specificity

Low immune cell specificity

Cell line specificity

Low cell line specificity

Interaction

Homodimer. May interact with CEBPB (By similarity). Interacts with EXOSC10.

Molecular function

Isomerase

More Types Infomation

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For Research Use Only. Not For Clinical Use.

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