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PTP4A3

This gene encodes a member of the protein-tyrosine phosphatase family. Protein tyrosine phosphatases are cell signaling molecules that play regulatory roles in a variety of cellular processes. Studies of this class of protein tyrosine phosphatase in mice demonstrates that they are prenylated in vivo, suggesting their association with cell plasma membrane. The encoded protein may enhance cell proliferation, and overexpression of this gene has been implicated in tumor metastasis. Alternative splicing results in multiple transcript variants.
Protein class

Enzymes, Metabolic proteins

Predicted location

Intracellular

Single cell type specificity

Cell type enhanced (Cardiomyocytes, Rod photoreceptor cells, Smooth muscle cells, Cone photoreceptor cells, Bipolar cells)

Immune cell specificity

Immune cell enhanced (neutrophil, non-classical monocyte)

Cell line specificity

Cell line enhanced (HDLM-2, Karpas-707, RPMI-8226, U-266/84)

Interaction

Interacts with tubulin.

Molecular function

Hydrolase, Protein phosphatase

More Types Infomation

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For Research Use Only. Not For Clinical Use.

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