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RALGDS

Guanine nucleotide dissociation stimulators (GDSs, or exchange factors), such as RALGDS, are effectors of Ras-related GTPases (see MIM 190020) that participate in signaling for a variety of cellular processes.
Protein class

RAS pathway related proteins

Predicted location

Intracellular

Single cell type specificity

Cell type enhanced (Urothelial cells)

Immune cell specificity

Group enriched (gdT-cell, T-reg, memory CD8 T-cell, memory CD4 T-cell, MAIT T-cell, naive CD8 T-cell, NK-cell)

Cell line specificity

Cell line enhanced (HDLM-2, SH-SY5Y)

Interaction

Interacts with RIT1 and RIT2 (By similarity). Interacts with OOG1 (By similarity). Interacts with TRAF3 (PubMed:27438768). Interacts with HRAS (By similarity).

Molecular function

Guanine-nucleotide releasing factor

More Types Infomation

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For Research Use Only. Not For Clinical Use.

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