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RARRES1

This gene was identified as a retinoid acid (RA) receptor-responsive gene. It encodes a type 1 membrane protein. The expression of this gene is upregulated by tazarotene as well as by retinoic acid receptors. The expression of this gene is found to be downregulated in prostate cancer, which is caused by the methylation of its promoter and CpG island. Alternatively spliced transcript variant encoding distinct isoforms have been observed. [provided by RefSeq, Jul 2008]
Predicted location

Intracellular

Single cell type specificity

Cell type enhanced (Urothelial cells, Club cells, Prostatic glandular cells, Basal prostatic cells)

Immune cell specificity

Not detected in immune cells

Cell line specificity

Cell line enriched (CAPAN-2)

Interaction

Interacts with AGBL2, KIF11 and MAPRE1.

More Types Infomation

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For Research Use Only. Not For Clinical Use.

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