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RGS12
This gene encodes a member of the 'regulator of G protein signaling' (RGS) gene family. The encoded protein may function as a guanosine triphosphatase (GTPase)-activating protein as well as a transcriptional repressor. This protein may play a role in tumorigenesis. Multiple transcript variants encoding distinct isoforms have been identified for this gene. Other alternative splice variants have been described but their biological nature has not been determined.
Protein class
Plasma proteins
Predicted location
Intracellular
Single cell type specificity
Cell type enhanced (Inhibitory neurons, Urothelial cells, Basal prostatic cells, Suprabasal keratinocytes)
Immune cell specificity
Low immune cell specificity
Cell line specificity
Low cell line specificity
Interaction
Interacts with GNAI1 (PubMed:18434541). Interacts with GNAI2 and GNAI3; the interactions are GDP-dependent (By similarity).
Molecular function
GTPase activation, Repressor, Signal transduction inhibitor
More Types Infomation
- Chicken Anti-RGS12 (ab2) Polyclonal IgY (BRD-0495MZ)
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- Species Reactivity: Human
- Type: Chicken antibody
- Application: WB
- Chicken Anti-RGS12 (ab1) Polyclonal IgY (BRD-0494MZ)
-
- Species Reactivity: Human, Mouse, Rat
- Type: Chicken antibody
- Application: WB
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For Research Use Only. Not For Clinical Use.