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RGS7

Protein class

Plasma proteins

Predicted location

Intracellular

Single cell type specificity

Cell type enhanced (Excitatory neurons, Inhibitory neurons, Oligodendrocyte precursor cells, Astrocytes)

Immune cell specificity

Not detected in immune cells

Cell line specificity

Cell line enhanced (BJ hTERT+ SV40 Large T+, HaCaT, hTERT-HME1, RH-30, SH-SY5Y, U-2 OS, U-251 MG)

Interaction

Interacts with PKD1; this prevents rapid proteasomal degradation (PubMed:10339594). Interacts with GNB5 (PubMed:10521509, PubMed:10339615). Interacts with RGS7BP, leading to regulate the subcellular location of the heterodimer formed with GNB5 (PubMed:15897264). Interacts (phosphorylated form) with 14-3-3 protein YWHAQ (PubMed:10862767). Interacts with SNAPIN (PubMed:12659861). Interacts with GNAI1 (PubMed:18434541). Interacts with GNAO1, GNAI3 and GNAZ (By similarity).

Molecular function

GTPase activation, Signal transduction inhibitor

More Types Infomation

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