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RNASE2

This is a non-secretory ribonuclease. It is a pyrimidine specific nuclease with a slight preference for U. Cytotoxin and helminthotoxin. Selectively chemotactic for dendritic cells. Possesses a wide variety of biological activities.
Protein class

Enzymes, Plasma proteins

Predicted location

Secreted

Single cell type specificity

Cell type enhanced (Kupffer cells, Macrophages, monocytes, Erythroid cells)

Immune cell specificity

Group enriched (eosinophil, basophil)

Cell line specificity

Group enriched (HL-60, NB-4, THP-1, U-937)

Interaction

Interacts with and forms a tight 1:1 complex with RNH1. Dimerization of two such complexes may occur.

Molecular function

Endonuclease, Hydrolase, Lyase, Nuclease

More Types Infomation

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For Research Use Only. Not For Clinical Use.

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