Enzymes, Metabolic proteins
Intracellular
Low cell type specificity
Low immune cell specificity
Low cell line specificity
Interacts with importin alpha, leading to stimulate both RNA-binding and methyltransferase activity (PubMed:11114884). Interaction with importin alpha and beta is required for its nuclear localization, importin beta dissociating in response to RanGTP, allowing RNMT-importin alpha to bind RNA substrates (PubMed:11114884). Interacts with elongating form of polymerase II and RNGTT (PubMed:9705270). Interacts with RAMAC, this interaction significantly enhances RNA-binding and cap methyltransferase activity (PubMed:22099306, Ref. 14).
Methyltransferase, RNA-binding, Transferase
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For Research Use Only. Not For Clinical Use.