Disease related genes, Human disease related genes, Nuclear receptors, Transcription factors
Intracellular
Cell type enhanced (Hepatocytes, Distal tubular cells, Proximal enterocytes)
Immune cell enriched (MAIT T-cell)
Cell line enhanced (HDLM-2, Karpas-707, MOLT-4, RPMI-8226, SK-BR-3, T-47d)
Interacts (via AF-2 motif) with the coactivator NCOA2 (via LXXLL motif) (PubMed:20211758). Interacts with the corepressor NCOR1 (By similarity). Interacts with CRY1 (PubMed:22170608). Interacts (via AF-2 motif) with the coactivators NCOA1 and PPARGC1A (via LXXLL motif) (By similarity). Interacts (via AF-2 motif) with PROX1 (By similarity). Interacts with FOXP3 (PubMed:18368049). Interacts with NR0B2 (By similarity).
Activator, Developmental protein, DNA-binding, Receptor
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For Research Use Only. Not For Clinical Use.