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RPS6KA1
Serine/threonine kinases may play a role in mediating growth factor and stress-induced activation of the transcription factor CREB.
Protein class
Cancer-related genes, Enzymes, Metabolic proteins, Plasma proteins
Predicted location
Intracellular
Single cell type specificity
Cell type enhanced (Proximal enterocytes, Distal enterocytes, NK-cells, monocytes)
Immune cell specificity
Low immune cell specificity
Cell line specificity
Cell line enhanced (HMC-1, U-937)
Interaction
Forms a complex with either MAPK1/ERK2 or MAPK3/ERK1 in quiescent cells. Transiently dissociates following mitogenic stimulation. Interacts with ETV1/ER81 and FGFR1. (Microbial infection) Interacts with Kaposi's sarcoma-associated herpesvirus/HHV-8 protein ORF45; this interaction allows RPS6KA1 activation.
Molecular function
Kinase, Serine/threonine-protein kinase, Transferase
More Types Infomation
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- Derivation: Mouse
- Species Reactivity: Human
- Type: Mouse IgG2a
- Application: WB, IHC
-
- Species Reactivity: Human, Mouse, Rat
- Type: Rabbit IgG
- Application: WB, IF, IHC, IP
-
- Species Reactivity: Human, Mouse, Rat
- Type: Rabbit IgG
- Application: WB, IF, IP
-
- Species Reactivity: Human
- Type: Mouse antibody
- Application: ELISA
-
- Derivation: Phage display library screening
- Species Reactivity: Human
- Type: IgG
- Application: ICC, WB
-
- Species Reactivity: Human, Mouse, Rat
- Type: Rabbit IgG
- Application: WB, IP
-
- Species Reactivity: Human, Mouse, Monkey
- Type: Mouse IgG
- Application: WB
-
- Derivation: Mouse
- Species Reactivity: Human, Mouse
- Type: Mouse IgG1, κ
- Application: WB
-
- Derivation: Mouse
- Species Reactivity: Human, Mouse, Monkey
- Type: Mouse IgG1
- Application: WB, IP
-
- Species Reactivity: Human
- Type: Rabbit IgG
- Application: ELISA, WB, IP
-
- Species Reactivity: Human
- Type: Rabbit IgG
- Application: ELISA, WB, IF, IP
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For Research Use Only. Not For Clinical Use.