Disease related genes, Human disease related genes
Membrane
Group enriched (Extravillous trophoblasts, Cytotrophoblasts, Syncytiotrophoblasts, Skeletal myocytes)
Group enriched (basophil, eosinophil, plasmacytoid DC)
Cell line enhanced (RH-30, RT4)
Interacts with isoform 1 but not isoform 3 of SPAST (PubMed:22232211). Interacts with BACE1 (PubMed:15286784). Interacts (via first transmembrane domain) with ARL6IP5/GTRAP3-18 (By similarity). Interacts (via N-terminus) with SLC1A1/EAAC1; the interaction promotes cell surface expression of SLC1A1 (By similarity). [Isoform RTN2-B]: Interacts with TMEM33.
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For Research Use Only. Not For Clinical Use.