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SDCCAG3
May be involved in modulation of TNF response. May be involved in presentation of TNFRSF1A on the cell surface (By similarity). Involved in the endosome-to-plasma membrane trafficking and recycling of SNX27-retromer-dependent cargo proteins, such as GLUT1 (PubMed:25278552). Involved in the regulation of cytokinesis; the function may involve PTPN13 and GIT1 (PubMed:23108400).
Predicted location
Intracellular
Single cell type specificity
Cell type enhanced (Theca cells, Endometrial stromal cells, Breast myoepithelial cells, Adipocytes, Granulosa cells, Pancreatic endocrine cells, Hofbauer cells, Breast glandular cells)
Immune cell specificity
Low immune cell specificity
Cell line specificity
Low cell line specificity
Interaction
Found in a complex with ENTR1, PTPN13 and GIT1 (PubMed:23108400). Interacts with PTPN13 (via the FERM domain) (PubMed:23108400). Interacts (via N-terminus) with GIT1 (via N- and C-terminus); this interaction is direct (PubMed:23108400). Interacts with NOD2 (PubMed:27812135). Interacts (via N-terminus) with IFT88 (PubMed:27767179). Interacts with VPS35 (PubMed:25278552).
More Types Infomation
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- Derivation: Mouse
- Species Reactivity: Human
- Type: Mouse IgG2b,, κ
- Application: WB, IP, IF, ELISA
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For Research Use Only. Not For Clinical Use.