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SERPINE2
This gene encodes a member of the serpin family of proteins, a group of proteins that inhibit serine proteases. Thrombin, urokinase, plasmin and trypsin are among the proteases that this family member can inhibit. This gene is a susceptibility gene for chronic obstructive pulmonary disease and for emphysema. Alternative splicing results in multiple transcript variants.
Protein class
Plasma proteins
Predicted location
Secreted
Single cell type specificity
Cell type enriched (Granulosa cells)
Immune cell specificity
Group enriched (NK-cell, naive CD4 T-cell, naive CD8 T-cell)
Cell line specificity
Cell line enhanced (BJ, fHDF/TERT166, SK-MEL-30, WM-115)
Molecular function
Developmental protein, Heparin-binding, Protease inhibitor, Serine protease inhibitor
More Types Infomation
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- Species Reactivity: Human
- Application: ELISA, WB
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- Derivation: Phage display library screening
- Species Reactivity: Human
- Type: IgG
- Application: WB
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For Research Use Only. Not For Clinical Use.