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SERPINF2
SERPINF2 encodes a member of the serpin family of serine protease inhibitors. The protein is a major inhibitor of plasmin, which degrades fibrin and various other proteins. Consequently, the proper function of this gene has a major role in regulating the blood clotting pathway. Mutations in this gene result in alpha-2-plasmin inhibitor deficiency, which is characterized by severe hemorrhagic diathesis.
Protein class
Candidate cardiovascular disease genes, Disease related genes, Human disease related genes, Plasma proteins
Predicted location
Secreted
Single cell type specificity
Cell type enriched (Hepatocytes)
Immune cell specificity
Immune cell enriched (plasmacytoid DC)
Cell line specificity
Cell line enriched (Hep G2)
Interaction
Forms protease inhibiting heterodimer with TMPRSS7.
Molecular function
Protease inhibitor, Serine protease inhibitor
More Types Infomation
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- Species Reactivity: Human
- Type: Mouse antibody
- Application: ELISA, IHC-P, WB
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- Species Reactivity: Human
- Type: IgG
- Application: FC
-
- Species Reactivity: Human
- Type: IgG
- Application: WB, ELISA, IP
- Recombinant Mouse Anti-Serpinf2 Antibody (4H9) (NEUT-1953CQ)
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- Species Reactivity: Mouse
- Type: IgG1, κ
- Application: ELISA, Inhib, WB
- Recombinant Mouse Anti-Serpinf2 Antibody (27C9) (NEUT-1952CQ)
-
- Species Reactivity: Mouse
- Type: IgG
- Application: ELISA, Inhib, WB
-
- Species Reactivity: Human
- Type: IgG
- Application: FC
-
- Species Reactivity: Mouse
- Type: IgG
- Application: ELISA
-
- Derivation: Phage display library screening
- Species Reactivity: Human
- Type: IgG
-
- Derivation: Mouse
- Species Reactivity: Human
- Type: Mouse IgG1
- Application: WB, ELISA
- Human Anti-SERPINF2 Recombinant Antibody (clone h77A3-2) (HPAB-A1332-YJ)
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- Derivation: Humanized
- Species Reactivity: Human
- Type: Humanized IgG1
- Application: ELISA, Inhib, RIA, IB, IA, FuncS
- Human Anti-SERPINF2 Recombinant Antibody (clone h77A3-1) (HPAB-A1331-YJ)
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- Derivation: Humanized
- Species Reactivity: Human
- Type: Humanized IgG1
- Application: ELISA, Inhib, RIA, IB, IA, FuncS
- Human Anti-SERPINF2 Recombinant Antibody (clone ch77A3) (HPAB-A1330-YJ)
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- Derivation: Chimeric (mouse/human)
- Species Reactivity: Human
- Type: Chimeric (mouse/human) IgG1
- Application: ELISA, Inhib, RIA, IB, IA, FuncS
- Mouse Anti-SERPINF2 Recombinant Antibody (clone 77A3) (HPAB-A1329-YJ)
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- Species Reactivity: Human
- Type: Mouse IgG
- Application: ELISA, Inhib, RIA, IB, IA, FuncS
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For Research Use Only. Not For Clinical Use.