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SGCB

Component of the sarcoglycan complex, a subcomplex of the dystrophin-glycoprotein complex which forms a link between the F-actin cytoskeleton and the extracellular matrix
Protein class

Disease related genes, Human disease related genes

Predicted location

Membrane

Single cell type specificity

Cell type enhanced (Late spermatids)

Immune cell specificity

Low immune cell specificity

Cell line specificity

Cell line enhanced (ASC diff)

Interaction

Cross-link to form 2 major subcomplexes: one consisting of SGCB, SGCD and SGCG and the other consisting of SGCB and SGCD. The association between SGCB and SGCG is particularly strong while SGCA is loosely associated with the other sarcoglycans (By similarity).

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For Research Use Only. Not For Clinical Use.

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