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SGIP1
SGIP1 functions as an endocytic protein that affects signaling by receptors in neuronal systems involved in energy homeostasis via its interaction with endophilins (see SH3GL3; MIM 603362) (Trevaskis et al., 2005 [PubMed 15919751] and Uezu et al., 2007 [PubMed 17626015]).[supplied by OMIM, Mar 2008]
Predicted location
Intracellular
Single cell type specificity
Group enriched (Oligodendrocyte precursor cells, Inhibitory neurons, Astrocytes, Oligodendrocytes, Cone photoreceptor cells, Rod photoreceptor cells, Excitatory neurons)
Immune cell specificity
Not detected in immune cells
Cell line specificity
Cell line enhanced (BJ, BJ hTERT+, fHDF/TERT166, hTERT-RPE1, RPTEC TERT1, SH-SY5Y, U-138 MG)
Interaction
Interacts with proteins essential or regulating the formation of functional clathrin-coated pits (Probable). Interacts with CANX (By similarity). Interacts with AP2A1 (By similarity). Interacts with EPS15 (PubMed:26822536). Interacts with SH3GL3 (PubMed:15919751). Interacts with AMPH (PubMed:20946875). Interacts with ITSN1 (via SH3 domains) (PubMed:20946875). Interacts with and REPS1 (PubMed:20946875).
More Types Infomation
- Recombinant Anti-Human SGIP1 Antibody (MOB-3872z)
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- Derivation: Mouse
- Species Reactivity: Human
- Type: IgG
- Application: WB, IP, FuncS
- Recombinant Anti-Human SGIP1 Antibody scFv Fragment (MOB-3872z-S(P))
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- Derivation: Mouse
- Species Reactivity: Human
- Type: scFv
- Application: FC, ELISA, FuncS
- Recombinant Anti-Human SGIP1 Antibody Fab Fragment (MOB-3872z-F(E))
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- Derivation: Mouse
- Species Reactivity: Human
- Type: Fab
- Application: FC, IP, FuncS
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- Species Reactivity: Human
- Application: WB, IHC-P, IHC-Fr, ICC, ICC/IF
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For Research Use Only. Not For Clinical Use.