Intracellular
Cell type enhanced (Excitatory neurons, Inhibitory neurons, Oligodendrocytes, Oligodendrocyte precursor cells)
Not detected in immune cells
Cell line enhanced (OE19, RPMI-8226, SCLC-21H, SH-SY5Y, U-266/84)
Interacts with RAB9A (GTP-bound form) and RAB9B (GTP-bound form); has much lower affinity for GDP-bound RAB9A and RAB9B (PubMed:22637480). Interacts with RAB3A, RAB4A, RAB5A, RAB8A, RAB11A, RAP1A, RAP1B, RAP2A and RAP2B. No interaction with RAB27A (PubMed:17509819).
GTPase activation
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For Research Use Only. Not For Clinical Use.