Intracellular
Cell type enhanced (Oligodendrocytes, Oligodendrocyte precursor cells)
Not detected in immune cells
Cell line enhanced (ASC diff, ASC TERT1, HSkMC)
Interacts with ADAM12. Isoform 4 and isoform 5 (but not isoform 1 and isoform 2) interact with ADAM9, ADAM10, ADAM15 and ADAM17. Interacts with SH3GL1 SH3 domain. Interacts via SH3 3 and SH3 4 or SH3 4 and SH3 5 domains with SOS2. Probably forms a trimeric complex with SH3GL1 and SOS2. Interacts with SH3YL1 (By similarity).
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For Research Use Only. Not For Clinical Use.