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SHC4
Protein class
RAS pathway related proteins
Predicted location
Intracellular
Single cell type specificity
Cell type enhanced (Oligodendrocytes, Oligodendrocyte precursor cells, Astrocytes)
Immune cell specificity
Not detected in immune cells
Cell line specificity
Group enriched (AN3-CA, SK-MEL-30, WM-115)
Interaction
Interacts (via PID domain) with phosphorylated MUSK (via NPXY motif); undergoes tyrosine phosphorylation downstream of activated MUSK. Interacts with GRB2; the interaction is dependent of Tyr-424 phosphorylation and increased by EGF.
More Types Infomation
Related Diseases
Colorectal Cancer
Endometrial Cancer
Hepatocellular Carcinoma
Non-small Cell Lung Cancer
Alcoholism
Related Signaling Pathways
ErbB Signaling Pathway
MAPK Signaling Pathway
PPAR Signaling Pathway
Ras Signaling Pathway
- Recombinant Mouse Anti-Human SHC4 Antibody (MOB-1858MZ)
-
- Species Reactivity: Human
- Type: Mouse antibody
- Application: WB
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For Research Use Only. Not For Clinical Use.