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SLC17A7

Enables inorganic phosphate transmembrane transporter activity and sodium:phosphate symporter activity. Involved in several processes, including neurotransmitter loading into synaptic vesicle; phosphate ion transport; and regulation of synaptic vesicle endocytosis. Located in excitatory synapse and presynaptic active zone. Is integral component of synaptic vesicle membrane. Is active in synaptic vesicle membrane. Biomarker of sciatic neuropathy and transient cerebral ischemia. Orthologous to human SLC17A7 (solute carrier family 17 member 7).
Protein class

Metabolic proteins, Transporters

Predicted location

Membrane

Single cell type specificity

Group enriched (Cone photoreceptor cells, Bipolar cells, Rod photoreceptor cells, Excitatory neurons)

Immune cell specificity

Not detected in immune cells

Cell line specificity

Cell line enhanced (HMC-1, K-562, REH, SCLC-21H)

Interaction

Interacts with SHANK3.

More Types Infomation

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For Research Use Only. Not For Clinical Use.

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