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SLC22A2

Polyspecific organic cation transporters in the liver, kidney, intestine, and other organs are critical for elimination of many endogenous small organic cations as well as a wide array of drugs and environmental toxins. This gene is one of three similar cation transporter genes located in a cluster on chromosome 6. The encoded protein contains twelve putative transmembrane domains and is a plasma integral membrane protein. It is found primarily in the kidney, where it may mediate the first step in cation reabsorption. [provided by RefSeq, Jul 2008]
Protein class

Metabolic proteins, Transporters

Predicted location

Membrane

Single cell type specificity

Group enriched (Proximal tubular cells, Distal tubular cells)

Immune cell specificity

Not detected in immune cells

Cell line specificity

Not detected

More Types Infomation

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For Research Use Only. Not For Clinical Use.

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