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SLC5A11

Involved in the sodium-dependent cotransport of myo-inositol (MI) with a Na(+):MI stoichiometry of 2:1. Exclusively responsible for apical MI transport and absorption in intestine. Also can transport D-chiro-inositol (DCI) but not L-fructose. Exhibits stereospecific cotransport of both D-glucose and D-xylose. May induce apoptosis through the TNF-alpha, PDCD1 pathway. May play a role in the regulation of MI concentration in serum, involving reabsorption in at least the proximal tubule of the kidney.
Protein class

Metabolic proteins, Transporters

Predicted location

Membrane

Single cell type specificity

Cell type enriched (Oligodendrocytes)

Immune cell specificity

Not detected in immune cells

Cell line specificity

Group enriched (Hep G2, Karpas-707)

More Types Infomation

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For Research Use Only. Not For Clinical Use.

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