TNFRSF8
The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is expressed by activated, but not by resting, T and B cells. TRAF2 and TRAF5 can interact with this receptor, and mediate the signal transduction that leads to the activation of NF-kappaB. This receptor is a positive regulator of apoptosis, and also has been shown to limit the proliferative potential of autoreactive CD8 effector T cells and protect the body against autoimmunity. Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported.
Derivation: Phage Display Library
Species Reactivity: Human
Type: Human Fab
Application: ELISA, WB
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Derivation: Phage Display Library
Species Reactivity: Human
Type: Human scFv
Application: ELISA, WB
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Species Reactivity: Human
Type: Human IgG1
Application: Activ, ELISA, FC, IF, IHC
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Derivation: Phage Display Library
Species Reactivity: Human
Type: Human IgG
Application: ELISA, WB
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Species Reactivity: Human
Type: Mouse antibody
Application: IHC
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Derivation: Mouse
Species Reactivity: Human
Type: Mouse IgG2b
Application: WB, FC, FuncS
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Species Reactivity: Human
Type: Human Fab
Application: FC, ELISA
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Species Reactivity: Human
Type: Human Fab
Application: FC, ELISA
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Species Reactivity: Human
Type: Mouse Fab
Application: ELISA
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Derivation: Chimeric
Species Reactivity: Human
Type: Human Fab
Application: F, IH
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Species Reactivity: Human
Type: Mouse Fab
Application: Inhib, ELISA, FC, IF, IHC
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Derivation: Humanized
Species Reactivity: Human
Type: Humanized Fab
Application: ELISA, FC, FuncS, Cyt
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Species Reactivity: Human
Type: Mouse Fab
Application: WB, ELISA
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Species Reactivity: Human
Type: Mouse Fab
Application: WB, ELISA, FC
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Species Reactivity: Human
Type: Mouse Fab
Application: ELISA, FC, WB
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Species Reactivity: Human
Type: Mouse Fab
Application: ELISA, FC, WB
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Species Reactivity: Human
Type: Human Fab
Application: FC, Cyt, FuncS
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Species Reactivity: Human
Type: Human Fab
Application: FC, Cyt
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Species Reactivity: Human
Type: Mouse Fab
Application: ELISA, FC, Cyt, FuncS
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Species Reactivity: Human
Type: Human Fab
Application: ELISA, FC, Cyt, FuncS
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For Research Use Only. Not For Clinical Use.