10-FnIII scaffold protein anti-Human Mesenchymal stem cell

Name: 10-FnIII scaffold protein anti-Human Mesenchymal stem cell
SKU: SFN-L009
Rating: 5 (1 reviews)

CAT#: SFN-L009

The tenth fibronectin type III domain (10Fn3) that bound mesenchymal stem cell was isolated from the library using Phage display technology. The fibronectin type III domain (FN3) is a small autonomous folding unit which occurs in many animal proteins involving in ligand binding. The β-sandwich structure of FN3 closely resembles that of immunoglobulin domains. After affinity maturation, 10Fn3 variants were identified having affinities for mesenchymal stem cell as determined by biosensor technology. It's potential to be used in diagnostic, research and therapeutic applications.

Specifications

Scaffold Name
10-FnIII

Origin
Fibronectin

Core Structure
β-sandwich of 7 β-strands

Variable Regions
2–3 Loops

Target
Mesenchymal stem cell

Species Reactivity
Human

Expression Host
BL21 (DE3) cells

Applications
ELISA; immunohistochemistry; Microscopy; Flow Cytometer; Western Blotting; Functional Study

Target

Alternative Names
Fibronectin; 10-FnIII; MSCs; human mesenchymal stem cell

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Datasheet

Datasheet - SFN-L009.pdf

MSDS

MSDS - SFN-L009.pdf

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