10-FnIII scaffold protein anti-Ubiquitin
CAT#: SFN-L028
The tenth fibronectin type III domain (10Fn3) that bound ubiquitin was isolated from the library using phage display technology. The fibronectin type III domain (FN3) is a small autonomous folding unit which occurs in many animal proteins involving in ligand binding. The β-sandwich structure of FN3 closely resembles that of immunoglobulin domains. After affinity maturation, 10Fn3 variants were identified having affinities (KD=27 nM) for ubiquitin as determined by biosensor technology. It's potential to be used in diagnostic, research and therapeutic applications.
Specifications
- Scaffold Name
- 10-FnIII
- Origin
- Fibronectin
- Core Structure
- β-sandwich of 7 β-strands
- Variable Regions
- 2–3 Loops
- Target
- Ubiquitin
- Expression Host
- E. coli
- Affinity Constant
- 27 nM
- Applications
- ELISA; immunohistochemistry; Microscopy; Flow Cytometer; Western Blotting; Functional Study
Target
- Alternative Names
- Fibronectin; 10-FnIII; ubiquitin
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See other products for "Ubiquitin"
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-1022 | Recombinant Anti-Ubiquitin Antibody | ELISA, WB, Neut, FuncS | IgG |
| ZG-0165C | Mouse Anti-Ubiquitin Recombinant Antibody (clone 5F1) | WB, IF, ICC, IHC-P | Mouse IgG |
| ZG-0166C | Mouse Anti-Ubiquitin Recombinant Antibody (clone 6G6) | WB, IHC-P, IF | Mouse IgG |
| ZG-460C | Mouse Anti-Ubiquitin Recombinant Antibody (clone C1) | ELISA, WB | Mouse IgG2a |
| VS-0224-XY137 | Mouse Anti-Ubiquitin Recombinant Antibody (VS-0224-XY137) | ELISA, WB | Mouse IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-1022-F(E) | Recombinant Anti-Ubiquitin Antibody Fab Fragment | IF, FuncS | Fab |
| MHH-1022-F(E) | Recombinant Human Anti-Ubiquitin Antibody Fab Fragment | ELISA, WB, Dot, FuncS | Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-1022-S(P) | Recombinant Anti-Ubiquitin Antibody scFv Fragment | FC, Neut, Funcs | scFv |
| MHH-1022-S(P) | Recombinant Human Anti-Ubiquitin Antibody scFv Fragment | ELISA, WB, FuncS | scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MHC-CN1297 | PE-A*29:02/Human Ubiquitin (KESTLHLVL) MHC Tetramer | FCM, IHC | |
| MHC-CN1298 | APC-A*29:02/Human Ubiquitin (KESTLHLVL) MHC Tetramer | FCM, IHC | |
| MHC-CN1299 | FITC-A*29:02/Human Ubiquitin (KESTLHLVL) MHC Tetramer | FCM, IHC | |
| MHC-CN1300 | A*29:02/Human Ubiquitin (KESTLHLVL) MHC Tetramer | FCM, IHC |
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