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    Popular Searches: Recombinant Antibody MHC Tetramer T cell Receptor Scaffold Protein

    PE-A*02:01/Human CD20 (SLFLGILSV) MHC Tetramer (CAT#: MHC-LC066)

    This product is a tetramer of biotinylated peptide/MHC complex with streptavidin mainly composed of CD20-derived peptide of SLFLGILSV sequence covering 188-196 and A*02:01 molecule. The pMHC tetramer recognizes human CD8 T cells, and can be used in the analysis of individual antigen-specific T cells.

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    Custom Production

    MHC tetramer custom production provides a vital tool for researchers seeking to understand and manipulate T-cell immunity with exceptional precision. Please specify your requirements, including peptide sequence, MHC allele, and desired fluorophore etc. We will respond as soon as possible with a tailored solution.

    Peptide Sequence *:
    Allele Requested *:
    Antigen Species:
    Antigen Molecule:
    Sequence Position:
    Form Requested *:
    Conjugation *:
    Size *:
    Comments:

    Disclaimer: Please note that the MHC reagents we offered have been produced with strict quality control (including gene sequencing, affinity purification, SDS-PAGE analysis, and verification of biotinylation), but many have not been confirmed to stain or activate specific T cells.

    We require custom production
    • Gene Expression
    • Datasheet
    • MSDS
    • COA
    Subcellular Location and Protein Expression
    Figure 1 IF staining of human cell line REH
    Figure 1 IF staining of human cell line REH
    (Immunofluorescent staining of human cell line REH shows localization to nucleoplasm & plasma membrane.)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/14341/1778_G3_5_selected.jpg
    Figure 2 IF staining of human cell line A-431
    Figure 2 IF staining of human cell line A-431
    (Immunofluorescent staining of human cell line A-431 shows localization to nucleoplasm & plasma membrane.)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/14341/201_H5_1_red_green.jpg
    Figure 3 IF staining of human cell line U-2 OS
    Figure 3 IF staining of human cell line U-2 OS
    (Immunofluorescent staining of human cell line U-2 OS shows localization to nucleoplasm & plasma membrane.)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/14341/202_H5_1_red_green.jpg
    Normal Tissue
    Figure 4 Colon
    Figure 4 Colon
    (Mucosal lymphoid cells
    Staining:Medium
    Intensity: Strong
    Quantity: <25%)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/14341/39081_A_7_3.jpg
    Figure 5 Bone marrow
    Figure 5 Bone marrow
    (Hematopoietic cells
    Staining:Medium
    Intensity: Strong
    Quantity: <25%
    Location: Cytoplasmic/membranous)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/14341/39081_B_4_4.jpg
    Figure 6 Lymph node
    Figure 6 Lymph node
    (Germinal center cells
    Staining:High
    Intensity: Strong
    Quantity:>75%
    Location: Cytoplasmic/membranous
    Non-germinal center cells
    Staining:Medium
    Intensity: Strong
    Quantity: <25%
    Location: Cytoplasmic/membranous)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/14341/39081_A_7_8.jpg
    RNA Expression
    Figure 7 RNA cell line category: Group enriched (Daudi, U-698)
    Figure 7 RNA cell line category: Group enriched (Daudi, U-698)
    (Cell lines ordered by descending RNA expression order.)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000156738-MS4A1

    Specifications

    • Allele
    • A*02:01
    • Class
    • Class I
    • MHC Species
    • Human
    • Antigen
    • CD20
    • Antigen Species
    • Human
    • Peptide
    • SLFLGILSV
    • Range
    • 188-196
    • Conjugate
    • PE
    • Application
    • FCM

    Target

    • Antigen Introduction
    • This gene encodes a member of the membrane-spanning 4A gene family. Members of this nascent protein family are characterized by common structural features and similar intron/exon splice boundaries and display unique expression patterns among hematopoietic cells and nonlymphoid tissues. This gene encodes a B-lymphocyte surface molecule which plays a role in the development and differentiation of B-cells into plasma cells. This family member is localized to 11q12, among a cluster of family members. Alternative splicing of this gene results in two transcript variants which encode the same protein.
    • Alternative Names
    • MS4A1; membrane spanning 4-domains A1; B1; S7; Bp35; CD20; CVID5; LEU-16

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