APC-A*02:01/CMV pp65 (NLVPMVATV) MHC Tetramer
CAT#: MHC-LC349
This product is a tetramer of biotinylated peptide/MHC complex with streptavidin mainly composed of CMV-derived peptide of NLVPMVATV sequence covering 495-503 and A*02:01 molecule. The pMHC tetramer recognizes human CD8 T cells, and can be used in the analysis of individual antigen-specific T cells.
Specifications
- Allele
- A*02:01
- Class
- Class I
- MHC Species
- Human
- Antigen
- CMV pp65
- Antigen Species
- CMV
- Peptide
- NLVPMVATV
- Range
- 495-503
- Conjugate
- APC
- Application
- FCM
Target
- Antigen Introduction
- Human cytomegalovirus is a species of the Cytomegalovirus genus of viruses, which in turn is a member of the viral family known as Herpesviridae or herpesviruses. It is typically abbreviated as HCMV or, commonly but more ambiguously, as CMV. It is also known as human herpesvirus-5 (HHV-5). pp65 (ppUL83), the major constituent of both virions and noninfectious particles called dense bodies, localizes predominantly to the nucleus after virus penetration and accumulates in both nucleus and cytoplasm as virus matures late in infection, where it may associate with a kinase.
- Alternative Names
- CMV pp65; Human cytomegalovirus pp65; UL83; lower matrix protein
- Gene ID
- 911829
- UniProt ID
- Q05320
REVIEWS AND Q&AS
CITATIONS
RESOURCES
DOWNLOADS
RELATED PRODUCTS
Inquiry
Navs
Customer Review
There are currently no Customer reviews or questions for MHC-LC349. Click the button above to contact us or submit your feedback about this product.
Enhances Multicolor Flow Cytometry
The compatibility of this tetramer with other fluorescent markers greatly improves our capability for comprehensive immune profiling. It supports detailed studies into T cell responses, a cornerstone for our viral immunology research.
Consistent and Reliable Performance
Offering reproducible results, this tetramer has become indispensable for our longitudinal studies assessing T cell functions over time. Its dependability is critical for generating data that drives our understanding of immune responses in CMV infections.
Q&As
-
Why is targeting CMV pp65 important in immunological studies?
A: pp65 is a major antigen of the CMV virus, commonly recognized by the immune system. Studying T cell responses to pp65 provides insights into viral control and is crucial for developing therapies for CMV-related disorders or post-transplant infections.
-
What is the primary application of the APC-A02:01/CMV pp65 MHC Tetramer?
A: This tetramer is predominantly used in flow cytometry to detect CMV-specific CD8+ T cells. It helps researchers study T cell-mediated immune responses, particularly in the context of cytomegalovirus (CMV) infections.
View the frequently asked questions answered by Creative Biolabs Support.
Submit Your Publication
Published with our product? Submit your paper and receive a 10% discount on your next order! Share your research to earn exclusive rewards.
Downloadable Resources
Download resources about recombinant antibody development and antibody engineering to boost your research.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
See other products for "CMV pp65"
Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PFBC-118 | Recombinant Human Anti-CMV pp65 Antibody Fab Fragment (MO61) | BL |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PSBC-118 | Recombinant Human Anti-CMV pp65 Antibody scFv Fragment (MO61) | BL | scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MRO-1561CQ | Recombinant Mouse Anti-CMV pp65 Antibody (MRO-1561CQ) | IF | Mouse antibody |
| MRO-1562CQ | Recombinant Mouse Anti-CMV pp65 Antibody (CMV100) | IF | Mouse antibody |
| MRO-1563CQ | Recombinant Mouse Anti-CMV pp65 Antibody (CMV101) | IF | Mouse antibody |
| MRO-1564CQ | Recombinant Mouse Anti-CMV pp65 Antibody (0885) | IF | Mouse antibody |
| MRO-1565CQ | Recombinant Mouse Anti-CMV pp65 Antibody (MRO-1565CQ) | WB, IF, ELISA | Mouse antibody |
Specific Inquiry
Add to compare
See Our Custom Production in Action
Popular Products
Application: ELISA, IP, FC, FuncS, Neut, IF, ICC
Application: IF, IP, Neut, FuncS, ELISA, FC, ICC
Application: FC, IP, ELISA, Neut, FuncS, IF, WB
Application: ELISA, FC, IP, FuncS, IF, Neut, ICC
-2-1.png)
Application: IP, IF, FuncS, FC, Neut, ELISA, IHC
Application: IF, IP, Neut, FuncS, ELISA, FC, ICC
Application: WB, Neut, FuncS
Application: ELISA, IHC, FC, IP, IF, Inhib
Application: ELISA, IHC, FC, IP, IF, FuncS
Application: ELISA, IHC, FC, IP, IF, FuncS
Application: ELISA, PD, Activ, PK, Stim
Application: ELISA, Neut, FuncS
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
Send Inquiry
This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.
