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    APC-A*02:01/Human EphA2 (TLADFDPRV) MHC Tetramer

    CAT#: MHC-LC146

    This product is a tetramer of biotinylated peptide/MHC complex with streptavidin mainly composed of EphA2-derived peptide of TLADFDPRV sequence covering 883-891 and A*02:01 molecule. The pMHC tetramer recognizes human CD8 T cells, and can be used in the analysis of individual antigen-specific T cells.

    Gene Expression
    ❮
    Figure 1 IF staining of human cell line A549 Figure 2 RNA cell line category: Cell line enhanced (CAPAN-2, PC-3, U-251 MG, WM-115)
    ❯

    Specifications

    • Allele
    • A*02:01
    • Class
    • Class I
    • MHC Species
    • Human
    • Antigen
    • EphA2
    • Antigen Species
    • Human
    • Peptide
    • TLADFDPRV
    • Range
    • 883-891
    • Conjugate
    • APC
    • Application
    • FCM

    Target

    • Antigen Introduction
    • This gene belongs to the ephrin receptor subfamily of the protein-tyrosine kinase family. EPH and EPH-related receptors have been implicated in mediating developmental events, particularly in the nervous system. Receptors in the EPH subfamily typically have a single kinase domain and an extracellular region containing a Cys-rich domain and 2 fibronectin type III repeats. The ephrin receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. This gene encodes a protein that binds ephrin-A ligands. Mutations in this gene are the cause of certain genetically-related cataract disorders.
    • Alternative Names
    • EPHA2; EPH receptor A2; ECK; CTPA; ARCC2; CTPP1; CTRCT6
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    Datasheet

    Datasheet - MHC-LC146.pdf

    MSDS

    MSDS - MHC-LC146.pdf

    COA

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