APC-A*02:01/Human gp100 (mutant) (IMDQVPFSV) MHC Tetramer
CAT#: MHC-LC101
This product is a tetramer of biotinylated peptide/MHC complex with streptavidin mainly composed of gp100 (mutant)-derived peptide of IMDQVPFSV sequence covering 209-217 and A*02:01 molecule. The pMHC tetramer recognizes human CD8 T cells, and can be used in the analysis of individual antigen-specific T cells.





Specifications
- Allele
- A*02:01
- Class
- Class I
- MHC Species
- Human
- Antigen
- gp100 (mutant)
- Antigen Species
- Human
- Peptide
- IMDQVPFSV
- Range
- 209-217
- Conjugate
- APC
- Application
- FCM
Target
- Antigen Introduction
- This gene encodes a melanocyte-specific type I transmembrane glycoprotein. The encoded protein is enriched in melanosomes, which are the melanin-producing organelles in melanocytes, and plays an essential role in the structural organization of premelanosomes. This protein is involved in generating internal matrix fibers that define the transition from Stage I to Stage II melanosomes. This protein undergoes a complex pattern of prosttranslational processing and modification that is essential to the proper functioning of the protein. A secreted form of this protein that is released by proteolytic ectodomain shedding may be used as a melanoma-specific serum marker. Alternate splicing results in multiple transcript variants.
- Alternative Names
- PMEL; premelanosome protein; P1; SI; SIL; ME20; P100; SILV; ME20M; gp100; ME20-M; PMEL17; D12S53E
- Gene ID
- 6490
- UniProt ID
- P40967
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Datasheet
MSDS
COA
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CAT | Product Name | Application | Type |
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HPAB-0046-LSX-F(E) | Mouse Anti-PMEL Recombinant Antibody; Fab Fragment (HPAB-0046-LSX-F(E)) | ELISA, WB, FC | Mouse Fab |
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