Products

Agalsidase beta (TP-021CL)

Recombinant human alpha-galactosidase A. The mature protein is composed of 2 subunits of 398 residues. Protein is glycosylated and produced by CHO cells      

  • Datasheet

Specifications
Classify
Protein therapeutics replacing a protein that is deficient or abnormal: Metabolic enzyme deficiencies
Therapeutic
Agalsidase-β (human a-galactosidase A)
Trade Name
Fabrazyme
Function
Enzyme that hydrolyzes globotriaosylceramide (GL3) and other glycosphingolipids, reducing deposition of these lipids in capillary endothelium of the kidney and certain other cell types
Examples of Clinical Use
Fabry disease; prevents accumulation of lipids that could lead to renal and cardiovascular complications
References
Synonyms
Agalsidase alfa, Alpha-D- galactoside galactohydrolase, Alpha-D-galactosidase A, Alpha-galactosidase A precursor, Melibiase
UniProt
P06280
Genbank
X14448

For lab research use only, not for diagnostic, therapeutic or any in vivo human use.

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