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Recombinant Anti-human ABL1 VHH Single Domain Antibody (CAT#: NAB-1-VHH)

Anti-human ABL1 VHH Single Domain Antibody is a recombinant protein produced in E. coli.

Host: Llama

Isotype: Llama VHH

Applications: This product is suitable for use in WB, ICC, ChiP, FA, ELISA and most other immunological methods.


See more Engineered Antibody products for ABL1
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Subcellular Location and Protein Expression

Figure 1 IF staining of human cell line A-431
(Immunofluorescent staining of human cell line A-431 shows localization to nucleoplasm & nuclear bodies.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/27280/259_B8_2_selected.jpg
Figure 2 IF staining of human cell line U-2 OS
(Immunofluorescent staining of human cell line U-2 OS shows localization to nucleoplasm.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/28409/497_A9_2_selected.jpg
Figure 3 IHC staining of human heart muscle
(Immunohistochemical staining of human heart muscle shows strong cytoplasmic positivity in myocytes.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/27251/ihc_selected.jpg
Figure 4 IHC staining of human prostate
(Immunohistochemical staining of human prostate shows cytoplasmic and membranous positivity in glandular cells.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/27280/ihc_selected.jpg
Figure 5 IHC staining of human adrenal gland
(Immunohistochemical staining of human adrenal gland shows strong nuclear positivity in cortical cells.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/28409/ihc_selected.jpg
Figure 6 IHC staining of human duodenum
(Immunohistochemical staining of human duodenum shows moderate cytoplasmic positivity in glandular cells.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/2686/ihc_selected.jpg
Figure 7 IF staining of human cell line U-251 MG
(Immunofluorescent staining of human cell line U-251 MG shows localization to nucleoplasm & nuclear bodies.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/27280/258_B8_1_red_green.jpg

Normal Tissue

Figure 8 Cerebral cortex
(Neuropil
Staining:Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/28409/61378_B_8_5.jpg
Figure 9 Adrenal gland
(Glandular cells
Staining:High
Intensity: Strong
Quantity: 75%-25%
Location: Cytoplasmic/membranous nuclear)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/28409/61378_B_5_5.jpg
Figure 10 Colon
(Endothelial cells
Staining:Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous
Glandular cells
Staining:Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous nuclear
Peripheral nerve/ganglion
Staining:Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/28409/61494_A_9_3.jpg
Figure 11 Liver
(Hepatocytes
Staining:Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous nuclear)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/28409/61494_A_9_4.jpg
Figure 12 Kidney
(Cells in glomeruli
Staining:Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/membranous nuclear
Cells in tubules
Staining:Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous nuclear)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/28409/61494_A_9_5.jpg
Figure 13 Testis
(Spermatogonia cells
Staining:Medium
Intensity: Moderate
Quantity: 75%-25%)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/28409/61494_A_6_6.jpg

RNA Expression

Figure 14 RNA cell line category: Low cell line specificity
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000097007-ABL1

Specifications

  • Immunogen
  • human ABL proto-oncogene 1, non-receptor tyrosine kinase
  • Host Species
  • Llama
  • Type
  • Llama VHH
  • Species Reactivity
  • Human
  • Molecule Class
  • VHH Single Domain Antibody
  • Applications
  • This product is suitable for use in WB, ICC, ChiP, FA, ELISA and most other immunological methods.

Product Property

  • Storage
  • At -20°C for one year.

Target

  • Alternative Names
  • ABL1; ABL proto-oncogene 1, non-receptor tyrosine kinase; ABL; JTK7; p150; c-ABL; v-abl; c-ABL1; bcr/abl; tyrosine-protein kinase ABL1

Related Resources

  • Related Signaling Pathways

Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Downloads

Download resources about recombinant antibody development and antibody engineering to boost your research.

See other products for "ABL1"

Recombinant Antibody

CAT Product Name Application Type
MOB-0964MZ Mouse Anti-ABL1 Recombinant Antibody (clone TQN439) IHC-P Mouse IgG1
ZG-0356F Mouse Anti-ABL1 Recombinant Antibody (ZG-0356F) WB, ELISA Mouse IgG

MHC Tetramer for Cancer

CAT Product Name Application Type
MHC-LC084 A*02:01/Human BCR-ABL (GVRGRVEEI) MHC Tetramer FCM
MHC-LC085 A*02:01/Human BCR-ABL (GVRGRVEEI) MHC Tetramer FCM
MHC-YF330 A*02:01/Human BCR-ABL (GVRGRVEEI) MHC Pentamer FCM
MHC-YF331 A*03:01/Human BCR-ABL 210 kD fusion protein (ATGFKQSSK) MHC Pentamer FCM
MHC-YF332 A*03:01/Human BCR-ABL 210 kD fusion protein (KQSSKALQR) MHC Pentamer FCM

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For Research Use Only. Not For Clinical Use.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

* Abbreviations
3D IHC3D Immunohistochemistry
ActivActivation
AgonistAgonist
ApopApoptosis
BABioassay
BIBioimaging
BlockBlocking
Cell ScreeningCell Screening
SeparationCell Separation
ChIPChromatin Immunoprecipitation
CMCDComplement Mediated Cell Depletion
CostimCostimulation
CytCytotoxicity
DepletionDepletion
DBDot Blot
EMElectron Microscopy
ELISAEnzyme-linked Immunosorbent Assay
ELISPOTEnzyme-linked Immunosorbent Spot
FCFlow Cytometry
FuncSFunctional Assay
GSGel Super Shift Assay
HAHemagglutination
IAImmunoassay
IBImmunoblotting
ICCImmunocytochemistry
IDImmunodiffusion
IFImmunofluorescence
IHCImmunohistochemistry
IHC-FrImmunohistochemistry-Frozen
IHC-PImmunohistochemistry-Paraffin
REImmunohistology - Resin Sections
IPImmunoprecipitation
IRMAImmunoradiometric Assay
SHIn situ hybridization
InhibInhibition
ICFCIntracellular Staining for Flow Cytometry
KO/KD-WBKnockout/Knockdown target confirmation by Western Blot
Live cell imagingLive cell imaging
CyTOF®Mass Cytometry
MeDIPMethylated DNA Immunoprecipitation
MultiplexMultiplex bead-based assay
NeutNeutralization
PPProtein Purification
PGProteogenomics
RIRadial Immunodiffusion
RIARadioimmunoassay
StimStimulation
SPRSurface Plasmon Resonance
TCTissue Culture
TBTurbidimetry
WBWestern Blot

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