Recombinant Human Antibody is capable of binding to ABO blood group trisaccharide, expressed in HEK 293 cells.
Figure 1 The reference (BSA)-Subtracted Ph dependence of the apparent KD for the interaction between scFv AC1001 and the BSA-BGA conjate.
This prediction was confirmed by BLI measurements, which showed a marked decrease in the apparent KD as the pH dropped below the pKa of histidine
Makeneni, S., Ji, Y., Watson, D. C., Young, N. M., & Woods, R. J. (2014). Predicting the origins of anti-blood group antibody specificity: a case study of the ABO A-and B-antigens. Frontiers in immunology, 5, 397.
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
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CAT | Product Name | Application | Type |
---|---|---|---|
PFBZ-006 | Human Anti-ABO Blood Group Trisaccharide Recombinant Antibody (clone AC1001); Fab Fragment | WB, IHC, IF, FuncS | Human IgM |
CAT | Product Name | Application | Type |
---|---|---|---|
PSBZ-006 | Human Anti-ABO Blood Group Trisaccharide Recombinant Antibody (clone AC1001); scFv Fragment | WB, IHC, IF, FuncS | Human scFv |
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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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