Hi-Affi™ Rabbit Anti-ACVR1 Recombinant Antibody (clone DS61AB)
CAT#: MOR-0061
Recombinant Rabbit anti-ACVR1 monoclonal antibody for WB, IP, excellent for producing superior results. Hi-Affi™ antibodies are developed from different sources, such as B cells of immunized animals, hybridoma, phage display library. The application of recombinant technology avoids the traditional ascitic fluid approach, which achieves the antibody generation in a humane way with much larger scale, greater specificity and sensitivity, and not susceptible to cell-line drift or lot-to-lot variation.
Gene Expression
Subcellular Location
Figure 1 IF staining of human cell line HEK 293
Immunofluorescent staining of human cell line HEK 293 shows localization to nucleoli & cytosol.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/46514/804_D7_1_selected.jpg
Normal Tissue
Figure 2 Cerebral cortex
Endothelial cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous Neuronal cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous nuclear
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/7505/21979_B_8_5.jpg
Normal Tissue
Figure 3 Colon
Endothelial cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous Glandular cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous Peripheral nerve/ganglion Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/7505/21979_A_9_3.jpg
Normal Tissue
Figure 4 Liver
Hepatocytes Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/7505/21979_A_8_4.jpg
Normal Tissue
Figure 5 Kidney
Cells in glomeruli Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous Cells in tubules Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/7505/21979_A_7_5.jpg
Normal Tissue
Figure 6 Testis
Cells in seminiferous ducts Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous Leydig cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/7505/21979_A_6_6.jpg
Normal Tissue
Figure 7 Smooth muscle
Smooth muscle cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/7505/21979_B_6_7.jpg
RNA Expression
Figure 8 RNA cell line category: Low cell line specificity
Cell lines ordered by descending RNA expression order
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000115170-ACVR1
❮
❯
Specifications
- Immunogen
- Synthetic peptide corresponding to amino acids within Human Activin Receptor Type IA.
- Host Species
- Rabbit
- Derivation
- Phage display library screening
- Type
- Rabbit IgG
- Species Reactivity
- Mouse, Rat, Human
- Clone
- DS61AB
- Applications
- WB, IP
- Conjugate
- Unconjugated
Product Property
- Purification
- Purified with Absolute Mag™ Protein A Agarose
- Purity
- >95% as determined by analysis by SDS-PAGE
- Format
- Liquid
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Target
- Alternative Names
- Activin A Receptor, Type I; Serine/Threonine-Protein Kinase Receptor R1; TGF-B Superfamily Receptor Type I; Activin Receptor-Like Kinase 2; Activin Receptor Type I; EC 2.7.11.30; ACVRLK2; SKR1; Activin A Receptor, Type II-Like Kinase 2; Hydroxyalkyl-Protein Kinase; EC 2.7.11; ACVR1A; ACTR-I; ACTRI; ALK-2; TSR-I; ALK2; TSRI; FOP
- Gene ID
- 90
- UniProt ID
- Q04771
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Downloadable Resources
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Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
See other products for "ACVR1"
Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0230-CN-F(E) | Human Anti-Acvr1 Recombinant Antibody; Fab Fragment (HPAB-0230-CN-F(E)) | ELISA, FC | Chimeric (Rat/Human) Fab |
| HPAB-0231-CN-F(E) | Human Anti-Acvr1 Recombinant Antibody; Fab Fragment (HPAB-0231-CN-F(E)) | ELISA, FC | Chimeric (Rat/Human) Fab |
| HPAB-0228-CN-F(E) | Rat Anti-Acvr1 Recombinant Antibody; Fab Fragment (HPAB-0228-CN-F(E)) | ELISA, FC | Rat Fab |
| HPAB-0229-CN-F(E) | Rat Anti-Acvr1 Recombinant Antibody; Fab Fragment (HPAB-0229-CN-F(E)) | ELISA, FC | Rat Fab |
| HPAB-0232-CN-F(E) | Human Anti-Acvr1 Recombinant Antibody; Fab Fragment (HPAB-0232-CN-F(E)) | ELISA, FC | Humanized Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0228-CN-S(P) | Rat Anti-Acvr1 Recombinant Antibody; scFv Fragment (HPAB-0228-CN-S(P)) | ELISA, FC | Rat scFv |
| HPAB-0229-CN-S(P) | Rat Anti-Acvr1 Recombinant Antibody; scFv Fragment (HPAB-0229-CN-S(P)) | ELISA, FC | Rat scFv |
| HPAB-0232-CN-S(P) | Human Anti-Acvr1 Recombinant Antibody; scFv Fragment (HPAB-0232-CN-S(P)) | ELISA, FC | Human scFv |
| HPAB-0233-CN-S(P) | Human Anti-Acvr1 Recombinant Antibody; scFv Fragment (HPAB-0233-CN-S(P)) | ELISA, FC | Human scFv |
| HPAB-0698LY-S(P) | Mouse Anti-ACVR1 Recombinant Antibody; scFv Fragment (HPAB-0698LY-S(P)) | ELISA, FC | Mouse scfv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0698LY | Mouse Anti-ACVR1 Recombinant Antibody (HPAB-0698LY) | ELISA, FC | Mouse IgG1 |
| HPAB-0699LY | Mouse Anti-ACVR1 Recombinant Antibody (HPAB-0699LY) | ELISA, FC | Mouse IgG1 |
| HPAB-0700LY | Human Anti-ACVR1 Recombinant Antibody (HPAB-0700LY) | ELISA, FC | Humanized IgG1 |
| HPAB-0701LY | Human Anti-ACVR1 Recombinant Antibody (HPAB-0701LY) | ELISA, FC | Humanized IgG1 |
| HPAB-0702LY | Human Anti-ACVR1 Recombinant Antibody (HPAB-0702LY) | ELISA, FC | Humanized IgG1 |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0325-XY36 | Anti-ACVR1 Immunohistochemistry Kit | IHC | |
| VS-0525-XY133 | Anti-Human ACVR1 Immunohistochemistry Kit | IHC |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0425-YC602 | Recombinant Anti-Acvr1 Vesicular Antibody, EV Displayed (VS-0425-YC602) | ELISA, FC, Cell-uptake |
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