Anti-Human ACVRL1 Recombinant Antibody (TAB-003ML)
CAT#: TAB-003ML
Recombinant monoclonal antibody to ACVRL1. It is a human monoclonal antibody that can be potentially used in the treatment of Mesothelioma, pleural malignant, Hepatocellular carcinoma (HCC).
Gene Expression
Normal Tissue
Figure 1 IHC staining of human cerebral cortex
Immunohistochemical staining of human cerebral cortex shows strong granular cytoplasmic positivity in neuronal cells.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/7041/ihc_selected.jpg
Normal Tissue
Figure 2 Cerebral cortex
Endothelial cells Staining: Low Intensity: Weak Quantity: 75%-25% Location: Cytoplasmic/ membranous Neuronal cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous Neuropil Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/7041/21213_B_7_5.jpg
Normal Tissue
Figure 3 Colon
Endothelial cells Staining: Low Intensity: Weak Quantity: 75%-25% Location: Cytoplasmic/ membranous Glandular cells Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/7041/21213_A_7_3.jpg
Normal Tissue
Figure 4 Gallbladder
Glandular cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/7041/21213_A_5_4.jpg
Normal Tissue
Figure 5 Kidney
Cells in tubules Staining: High Intensity: Strong Quantity: 75%-25% Location: Cytoplasmic/ membranous nuclear
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/7041/21213_A_8_5.jpg
Normal Tissue
Figure 6 Testis
Elongated or late spermatids Staining: High Intensity: Strong Quantity:>75% Leydig cells Staining: Low Intensity: Weak Quantity:>75% Round or early spermatids Staining: High Intensity: Strong Quantity:>75%
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/7041/21213_A_6_6.jpg
Normal Tissue
Figure 7 Lymph node
Germinal center cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous Non-germinal center cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/7041/21213_A_9_8.jpg
RNA Expression
Figure 8 RNA cell line category: Cell line enhanced (ASC diff, ASC TERT1, EFO-21, HUVEC TERT2, TIME)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000139567-ACVRL1
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Specifications
- Immunogen
- The details of the immunogen for this antibody are not available.
- Host Species
- Human
- Derivation
- Human
- Type
- IgG2, κ
- Specificity
- Human ACVRL1
- Species Reactivity
- Human
- Applications
- Used for immunoassay techniques such as: Enzyme-Linked Immunosorbent Assay; Immunohistochemistry; Immunofluorescence; Immunoprecipitation; Flow Cytometry; Inhibition
- Conjugate
- Unconjugated
- Related Disease
- Mesothelioma, pleural malignant, Hepatocellular carcinoma (HCC)
Product Property
- Purity
- > 95% as determined by SDS-PAGE
- Storage
- Store at -20°C for long-term storage. Avoid freeze/thaw cycles.
Target
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Biosimilar Overview
Please refer to Ascrinvacumab Overview to learn more about the mechanism of action, clinical projects, and approved drugs of Ascrinvacumab.
Downloadable Resources
Download resources about recombinant antibody development and antibody engineering to boost your research.
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
Protocol & Troubleshooting
We have outlined the assay protocols, covering reagents, solutions, procedures, and troubleshooting tips for common issues in order to better assist clients in conducting experiments with our products. View the full list of Protocol & Troubleshooting.
See other products for "ACVRL1"
Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-0065 | Hi-Affi™ Rabbit Anti-ACVRL1 Recombinant Antibody (clone DS65AB) | ELISA | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0136-CN | Human Anti-ACVRL1 Recombinant Antibody (clone MOR05444) | ELISA, IHC | Human IgG1 |
| HPAB-0137-CN | Human Anti-ACVRL1 Recombinant Antibody (clone MOR05377) | ELISA, IHC | Human IgG1 |
| HPAB-J0024-YC | Human Anti-ACVRL1 Recombinant Antibody (HPAB-J0024-YC) | ELISA, FC, WB | Human IgG1 |
| HPAB-J0025-YC | Human Anti-ACVRL1 Recombinant Antibody (HPAB-J0025-YC) | ELISA, FC, WB | Human IgG |
| HPAB-J0026-YC | Human Anti-ACVRL1 Recombinant Antibody (HPAB-J0026-YC) | ELISA, FC, WB, Inhib, FuncS | Human IgG1 |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0136-CN-F(E) | Human Anti-ACVRL1 Recombinant Antibody (clone MOR05444); Fab Fragment | ELISA, IHC | Human Fab |
| HPAB-0137-CN-F(E) | Human Anti-ACVRL1 Recombinant Antibody (clone MOR05377); Fab Fragment | ELISA, IHC | Human Fab |
| HPAB-J0024-YC-F(E) | Human Anti-ACVRL1 Recombinant Antibody; Fab Fragment (HPAB-J0024-YC-F(E)) | ELISA, FC, WB | Human Fab |
| HPAB-J0025-YC-F(E) | Human Anti-ACVRL1 Recombinant Antibody; Fab Fragment (HPAB-J0025-YC-F(E)) | ELISA, FC, WB | Human Fab |
| HPAB-J0026-YC-F(E) | Human Anti-ACVRL1 Recombinant Antibody; Fab Fragment (HPAB-J0026-YC-F(E)) | ELISA, FC, WB, Inhib, FuncS | Human Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| AFC-TAB-003ML | Afuco™ Anti-ACVRL1 ADCC Recombinant Antibody, ADCC Enhanced | ELISA, IHC, FC, IP, IF, Inhib | ADCC enhanced antibody |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-J0024-YC-S(P) | Human Anti-ACVRL1 Recombinant Antibody; scFv Fragment (HPAB-J0024-YC-S(P)) | ELISA, FC, WB | Human scFv |
| HPAB-J0025-YC-S(P) | Human Anti-ACVRL1 Recombinant Antibody; scFv Fragment (HPAB-J0025-YC-S(P)) | ELISA, FC, WB | Human scFv |
| HPAB-J0026-YC-S(P) | Human Anti-ACVRL1 Recombinant Antibody; scFv Fragment (HPAB-J0026-YC-S(P)) | ELISA, FC, WB, Inhib, FuncS | Human scFv |
| HPAB-J0027-YC-S(P) | Human Anti-ACVRL1 Recombinant Antibody; scFv Fragment (HPAB-J0027-YC-S(P)) | ELISA | Human scFv |
| HPAB-J0028-YC-S(P) | Human Anti-ACVRL1 Recombinant Antibody; scFv Fragment (HPAB-J0028-YC-S(P)) | ELISA, FC, WB | Human scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0724-YC1261 | AbPlus™ Anti-ACVRL1 Magnetic Beads (VS-0724-YC1261) | IP, Protein Purification |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0325-FY91 | Human Anti-ACVRL1 (clone MOR05377) scFv-Fc Chimera | ELISA, IHC | Human IgG1, scFv-Fc |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0425-YC491 | Recombinant Anti-ACVRL1 Vesicular Antibody, EV Displayed (VS-0425-YC491) | ELISA, FC, Cell-uptake |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-XY141 | Anti-ACVRL1 Immunohistochemistry Kit | IHC |
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