Anti-Human AChR Recombinant Antibody (P90-65) (CAT#: TAB-0637CLV)

The anti-AChR antibody target acetylcholine receptor of which the high-level re-expression can occur after birth following denervation, including denervating neuromuscular diseases. The antibody can be used in the treatment of rhabdomyosarcoma.


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IF

Figure 1 Immortalized thymic B cell clones produce striational antibodies.

Figure 1 Immortalized thymic B cell clones produce striational antibodies.

Monkey muscle tissue was stained by immunofluorescence with culture supernatants (non-concentrated) of immortalized B cell clones.

Vrolix, K., Fraussen, J., Molenaar, P. C., Losen, M., Somers, V., Stinissen, P., ... & Martinez-Martinez, P. (2010). The auto-antigen repertoire in myasthenia gravis. Autoimmunity, 43(5-6), 380-400.

RIA

Figure 2 Immortalized B cell clones produce anti-human AChR antibodies.

Figure 2 Immortalized B cell clones produce anti-human AChR antibodies.

Specificity of immortalized B cell clones against human AChR was tested by RIA using AChR
isolated from the TE 671 cell line.

Vrolix, K., Fraussen, J., Molenaar, P. C., Losen, M., Somers, V., Stinissen, P., ... & Martinez-Martinez, P. (2010). The auto-antigen repertoire in myasthenia gravis. Autoimmunity, 43(5-6), 380-400.


Specifications

  • Host Species
  • Human
  • Derivation
  • Immortalized B cell clone
  • Type
  • Fully Human antibody
  • Specificity
  • Human
  • Clone
  • P90-65
  • Applications
  • RIA, IF
  • Related Disease
  • Rhabdomyosarcoma

Applications

  • Application Notes
  • The AChR antibody has been reported in applications of Immunofluorescence, Radioimmunoassay.

Target

  • Alternative Names
  • AChR; acetylcholine receptor

Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

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For Research Use Only. Not For Clinical Use.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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