Afuco™ Anti-Human ADCYAP1R1 ADCC Recombinant Antibody, ADCC Enhanced
CAT#: AFC-018CL
Anti-ADCYAP1R1 ADCC Enhanced Antibody is an ADCC enhanced antibody produced by our Afuco™ platform. The antibodies can inhibit binding of PAC1 to PACAP, and are useful in a number of PAC1 related disorders, including the treatment and/or prevention of headache disorders, including migraine and cluster headache.
Gene Expression
Subcellular Location
Figure 1 IF staining of human cell line SH-SY5Y
Immunofluorescent staining of human cell line SH-SY5Y shows localization to vesicles.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/30739/1735_E10_1_selected.jpg
Normal Tissue
Figure 2 High expression in cerebral cortex
Neuropil Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/49877/113058_B_7_5.jpg
Normal Tissue
Figure 3 Colon
Endothelial cells Staining: Low Intensity: Weak Quantity:>75% Location: Cytoplasmic/ membranous Glandular cells Staining: Low Intensity: Weak Quantity: 75%-25% Location: Cytoplasmic/ membranous nuclear Peripheral nerve/ganglion Staining: Low Intensity: Weak Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/49877/113058_A_9_3.jpg
Normal Tissue
Figure 4 Kidney
Cells in glomeruli Staining: Low Intensity: Weak Quantity: 75%-25% Location: Cytoplasmic/ membranous Cells in tubules Staining: Low Intensity: Weak Quantity: 75%-25% Location: Cytoplasmic/ membranous nuclear
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/49877/113058_A_9_5.jpg
Normal Tissue
Figure 5 Testis
Leydig cells Staining: Low Intensity: Weak Quantity:>75% Location: Cytoplasmic/ membranous nuclear
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/49877/113058_A_4_6.jpg
RNA Expression
Figure 6 RNA cell line category: Cell line enhanced (AF22, NTERA-2, SCLC-21H, SH-SY5Y)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000078549-ADCYAP1R1
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Specifications
- Host Species
- Human
- Derivation
- Human
- Type
- ADCC enhanced antibody
- Species Reactivity
- Human
- Related Disease
- Migraine
Product Property
- Purity
- 90–95% (SDS-PAGE)
- Storage
- Short term: store at 4°C (over 6 months), long term: -20°C or -80°C.
Target
- Alternative Names
- ADCYAP1R1; adenylate cyclase activating polypeptide 1 (pituitary) receptor type I; PAC1; PAC1R; PACAPR; PACAPRI; pituitary adenylate cyclase-activating polypeptide type I receptor; PACAP-R1; PACAP receptor 1; PACAP type I receptor; pituitary adenylate cyclase activating polypeptide 1 receptor type I Hiphop
- Gene ID
- 117
- UniProt ID
- A0A090N8F8
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Downloadable Resources
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Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-3850z | Mouse Anti-ADCYAP1R1 Recombinant Antibody (clone 15H5) | WB, IP, ELISA | Mouse IgG1, κ |
| MOB-1526CT | Mouse Anti-ADCYAP1R1 Recombinant Antibody (clone EML304) | IF, WB | Mouse IgG1 |
| HPAB-0039CQ | Human Anti-ADCYAP1R1 Recombinant Antibody (HPAB-0039CQ) | ELISA, Block | Human IgG1, κ |
| HPAB-0431-YJ | Human Anti-ADCYAP1R1 Recombinant Antibody (HPAB-0431-YJ) | Block, FuncS | Human IgG2, κ |
| VS-0923-FY253 | Recombinant Human Anti-ADCYAP1R1 Antibody (clone Zelminemab) | Inhib | Human IgG1, kappa |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-0917CL | Anti-Human ADCYAP1R1 Recombinant Antibody (2C) | Competitive ELISA | |
| TAB-0917CL-S(P) | Anti-Human ADCYAP1R1 Recombinant Antibody scFv Fragment (2C) | Competitive ELISA | |
| TAB-0917CL-F(E) | Anti-Human ADCYAP1R1 Recombinant Antibody Fab Fragment (2C) | Competitive ELISA |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-0918CL | Human Anti-ADCYAP1R1 Recombinant Antibody (TAB-0918CL) | ChIP | Human IgG1 |
| TAB-0919CL | Human Anti-ADCYAP1R1 Recombinant Antibody (TAB-0919CL) | cAMP functional assay | Human IgG2 |
| TAB-0918CL-S(P) | Human Anti-ADCYAP1R1 Recombinant Antibody; scFv Fragment (TAB-0918CL-S(P)) | cAMP functional assay | Human scFv |
| TAB-0918CL-F(E) | Human Anti-ADCYAP1R1 Recombinant Antibody; Fab Fragment (TAB-0918CL-F(E)) | cAMP functional assay | Human Fab |
| TAB-0919CL-F(E) | Human Anti-ADCYAP1R1 Recombinant Antibody; Fab Fragment (TAB-0919CL-F(E)) | cAMP functional assay | Human Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| Gly-189LC | Recombinant Anti-Human ADCYAP1R1 Antibody (Non-glycosylated) | ELISA | Human antibody |
| Gly-190LC | Recombinant Anti-Human ADCYAP1R1 Antibody (Non-glycosylated) | ELISA | Human antibody |
| Gly-191LC | Recombinant Anti-Human ADCYAP1R1 Antibody (Non-glycosylated) | ELISA | Human antibody |
| Gly-192LC | Recombinant Anti-Human ADCYAP1R1 Antibody (Non-glycosylated) | ELISA | Human antibody |
| Gly-193LC | Recombinant Anti-Human ADCYAP1R1 Antibody (Non-glycosylated) | ELISA | Human antibody |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0039CQ-S(P) | Human Anti-ADCYAP1R1 Recombinant Antibody; scFv Fragment (HPAB-0039CQ-S(P)) | ELISA, Block | Human scFv |
| HPAB-0431-YJ-S(P) | Human Anti-ADCYAP1R1 Recombinant Antibody; scFv Fragment (HPAB-0431-YJ-S(P)) | Block, FuncS | Human scFv |
| HPAB-0432-YJ-S(P) | Human Anti-ADCYAP1R1 Recombinant Antibody; scFv Fragment (HPAB-0432-YJ-S(P)) | Block, FuncS | Human scFv |
| HPAB-0437YY-S(P) | Human Anti-ADCYAP1R1 Recombinant Antibody; scFv Fragment (HPAB-0437YY-S(P)) | Neut | Human scFv |
| HPAB-0440YY-S(P) | Human Anti-ADCYAP1R1 Recombinant Antibody; scFv Fragment (HPAB-0440YY-S(P)) | Neut | Human scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0039CQ-F(E) | Human Anti-ADCYAP1R1 Recombinant Antibody; Fab Fragment (HPAB-0039CQ-F(E)) | ELISA, Block | Human Fab, κ |
| HPAB-0431-YJ-F(E) | Human Anti-ADCYAP1R1 Recombinant Antibody; Fab Fragment (HPAB-0431-YJ-F(E)) | Block, FuncS | Human Fab |
| HPAB-0432-YJ-F(E) | Human Anti-ADCYAP1R1 Recombinant Antibody; Fab Fragment (HPAB-0432-YJ-F(E)) | Block, FuncS | Human Fab |
| HPAB-0437YY-F(E) | Human Anti-ADCYAP1R1 Recombinant Antibody; Fab Fragment (HPAB-0437YY-F(E)) | Neut | Humanized Fab |
| HPAB-0440YY-F(E) | Human Anti-ADCYAP1R1 Recombinant Antibody; Fab Fragment (HPAB-0440YY-F(E)) | Neut | Humanized Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0424-XY7 | AbPlus™ Anti-ADCYAP1R1 Magnetic Beads (VS-0424-XY7) | ChIP, Protein Purification |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0425-YC565 | Recombinant Anti-ADCYAP1R1 Vesicular Antibody, EV Displayed (VS-0425-YC565) | ELISA, FC, Neut, Cell-uptake |
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