Afuco™ Anti-Human ADCYAP1R1 ADCC Recombinant Antibody, ADCC Enhanced (CAT#: AFC-018CL)
Anti-ADCYAP1R1 ADCC Enhanced Antibody is an ADCC enhanced antibody produced by our Afuco™ platform. The antibodies can inhibit binding of PAC1 to PACAP, and are useful in a number of PAC1 related disorders, including the treatment and/or prevention of headache disorders, including migraine and cluster headache.
Specific Inquiry
Custom Production
We specialize in custom recombinant antibody production, offering seamless execution from provided sequences to high-quality antibody deliverables, ensuring optimal yield and purity.
We require custom production
Subcellular Location
Normal Tissue
RNA Expression
Figure 1 IF staining of human cell line SH-SY5Y
(Immunofluorescent staining of human cell line SH-SY5Y shows localization to vesicles.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/30739/1735_E10_1_selected.jpg
(Immunofluorescent staining of human cell line SH-SY5Y shows localization to vesicles.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/30739/1735_E10_1_selected.jpg
Figure 2 High expression in cerebral cortex
(Neuropil Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/49877/113058_B_7_5.jpg
(Neuropil Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/49877/113058_B_7_5.jpg
Figure 3 Colon
(Endothelial cells Staining: Low Intensity: Weak Quantity:>75% Location: Cytoplasmic/ membranous Glandular cells Staining: Low Intensity: Weak Quantity: 75%-25% Location: Cytoplasmic/ membranous nuclear Peripheral nerve/ganglion Staining: Low Intensity: Weak Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/49877/113058_A_9_3.jpg
(Endothelial cells Staining: Low Intensity: Weak Quantity:>75% Location: Cytoplasmic/ membranous Glandular cells Staining: Low Intensity: Weak Quantity: 75%-25% Location: Cytoplasmic/ membranous nuclear Peripheral nerve/ganglion Staining: Low Intensity: Weak Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/49877/113058_A_9_3.jpg
Figure 4 Kidney
(Cells in glomeruli Staining: Low Intensity: Weak Quantity: 75%-25% Location: Cytoplasmic/ membranous Cells in tubules Staining: Low Intensity: Weak Quantity: 75%-25% Location: Cytoplasmic/ membranous nuclear)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/49877/113058_A_9_5.jpg
(Cells in glomeruli Staining: Low Intensity: Weak Quantity: 75%-25% Location: Cytoplasmic/ membranous Cells in tubules Staining: Low Intensity: Weak Quantity: 75%-25% Location: Cytoplasmic/ membranous nuclear)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/49877/113058_A_9_5.jpg
Figure 5 Testis
(Leydig cells Staining: Low Intensity: Weak Quantity:>75% Location: Cytoplasmic/ membranous nuclear)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/49877/113058_A_4_6.jpg
(Leydig cells Staining: Low Intensity: Weak Quantity:>75% Location: Cytoplasmic/ membranous nuclear)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/49877/113058_A_4_6.jpg
Figure 6 RNA cell line category: Cell line enhanced (AF22, NTERA-2, SCLC-21H, SH-SY5Y)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000078549-ADCYAP1R1
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000078549-ADCYAP1R1
Specifications
- Host Species
- Human
- Derivation
- Human
- Type
- ADCC enhanced antibody
- Species Reactivity
- Human
- Related Disease
- Migraine
Product Property
- Purity
- 90–95% (SDS-PAGE)
- Storage
- Short term: store at 4°C (over 6 months), long term: -20°C or -80°C.
Target
- Alternative Names
- ADCYAP1R1; adenylate cyclase activating polypeptide 1 (pituitary) receptor type I; PAC1; PAC1R; PACAPR; PACAPRI; pituitary adenylate cyclase-activating polypeptide type I receptor; PACAP-R1; PACAP receptor 1; PACAP type I receptor; pituitary adenylate cyclase activating polypeptide 1 receptor type I Hiphop
- Gene ID
- 117
- UniProt ID
- A0A090N8F8
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
See other products for "ADCYAP1R1"
Select a product category from the dropdown menu below to view related products.
Please select product type
Mouse Antibody Products
Human Antibody Products
Deglycosylated Antibody Products
IgG Antibody Products
ScFv Antibody Products
Fab Antibody Products
Antibody Magnetic Beads
Extracellular Vesicle (EV) Antibody Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-0917CL | Anti-Human ADCYAP1R1 Recombinant Antibody (2C) | Competitive ELISA | |
| TAB-0917CL-S(P) | Anti-Human ADCYAP1R1 Recombinant Antibody scFv Fragment (2C) | Competitive ELISA | |
| TAB-0917CL-F(E) | Anti-Human ADCYAP1R1 Recombinant Antibody Fab Fragment (2C) | Competitive ELISA |
Customer Reviews and Q&As
There are currently no Customer reviews or questions for AFC-018CL. Click the button above to contact us or submit your feedback about this product.
Popular products with customers
Application: WB, IF, IP, Neut, FuncS, ELISA, FC
Application: Neut, ELISA, IF, IP, FuncS, FC, ICC
Application: WB, FuncS, IF, Neut, ELISA, FC, IP
Application: Inhib, Cyt
Application: FuncS, IF, Neut, ELISA, FC, IP, WB
Application: WB, ELISA, FC, IP, FuncS, IF, Neut
Application: WB, Neut, ELISA, IF, IP, FuncS, FC
Application: WB, IF, FuncS
Application: ELISA, FC, FuncS
Application: ELISA, FC, FuncS
For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
Send Inquiry
This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.
