Afuco™ Anti-Human AGTR1 ADCC Recombinant Antibody, ADCC Enhanced (CAT#: AFC-028CL)
Anti-AGTR1 ADCC Enhanced Antibody is an ADCC enhanced antibody produced by our Afuco™ platform. The use of monoclonal antibodies to the angiotensin-II type-I receptor is for the treatment of cancer and vascular smooth muscle cell proliferation.
Specific Inquiry
Subcellular Location
Normal Tissue
RNA Expression
Figure 1 IF staining of human cell line ASC TERT1
(Immunofluorescent staining of human cell line ASC TERT1 shows localization to vesicles.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/3596/1749_G1_8_cr580497afc9e61_selected.jpg
(Immunofluorescent staining of human cell line ASC TERT1 shows localization to vesicles.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/3596/1749_G1_8_cr580497afc9e61_selected.jpg
Figure 2 High expression in adipose tissue
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/3596/11017_B_3_7_val_selected.jpg
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/3596/11017_B_3_7_val_selected.jpg
Figure 3 Low expression in cerebral cortex
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/3596/11017_B_7_5_val_selected.jpg
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/3596/11017_B_7_5_val_selected.jpg
Figure 4 Cerebral cortex
(Endothelial cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/3596/11017_B_7_5.jpg
(Endothelial cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/3596/11017_B_7_5.jpg
Figure 5 RNA cell line category: Cell line enhanced (ASC diff, ASC TERT1, BJ hTERT+ SV40 Large T+, HBF TERT88, HSkMC)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000144891-AGTR1
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000144891-AGTR1
Specifications
- Host Species
- Humanized
- Derivation
- Humanized
- Type
- ADCC enhanced antibody
- Species Reactivity
- Human
- Related Disease
- Cancer
Product Property
- Purity
- >95%, by SDS-PAGE with Coomassie Brilliant Blue staining
- Storage
- ≤1 year at -20°C.
Target
- Alternative Names
- AGTR1; angiotensin II receptor, type 1; AT1; AG2S; AT1B; AT1R; AT1AR; AT1BR; AT2R1; HAT1R; AGTR1B; Angiotensin-II type-I receptor
- Gene ID
- 185
- UniProt ID
- P30556
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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IgG Antibody Products
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Single Domain Antibody Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-1660z | Mouse Anti-AGTR1 Recombinant Antibody (MOB-1660z) | ELISA, WB, IP, IF, IHC, FC | Mouse IgG1, κ |
| HPAB-J0030-YC | Mouse Anti-AGTR1 Recombinant Antibody (HPAB-J0030-YC) | ELISA, FuncS | Mouse IgG |
| HPAB-J0031-YC | Mouse Anti-AGTR1 Recombinant Antibody (HPAB-J0031-YC) | ELISA | Mouse IgG |
| HPAB-J0032-YC | Human Anti-AGTR1 Recombinant Antibody (HPAB-J0032-YC) | ELISA | Humanized IgG |
| HPAB-J0033-YC | Human Anti-AGTR1 Recombinant Antibody (HPAB-J0033-YC) | ELISA | Humanized IgG |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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