Mouse Anti-APP Recombinant Antibody (clone WO2) (CAT#: PABL-404)
Recombinant Mouse Antibody (WO2) is capable of binding to APP. This recognizes Aβ residues 3–7 the N-terminus of the APP.
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We specialize in custom recombinant antibody production, offering seamless execution from provided sequences to high-quality antibody deliverables, ensuring optimal yield and purity.
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Figure 1 Western blot analysis of monoclonal antibody WO2 in transgenic Tg2576 and background control strain (C57B6 X SJL) mice at 4, 8 and 12 months of age.
Brains were homogenized as described and extracts applied to 15% Tris‐tricine SDS–PAGE. The migration of the molecular weight markers are shown. Data represents the increase in total Aβ levels in Tg2576 mice as they age.
Fodero, L. R., Sáez‐Valero, J., McLean, C. A., Martins, R. N., Beyreuther, K., Masters, C. L., ... & Small, D. H. (2002). Altered glycosylation of acetylcholinesterase in APP (SW) Tg2576 transgenic mice occurs prior to amyloid plaque deposition. Journal of neurochemistry, 81(3), 441-448.
Specifications
- Immunogen
- Human amyloid beta (A4) precursor protein
- Host Species
- Mouse
- Derivation
- Mouse
- Type
- Mouse IgG
- Specificity
- APP
- Species Reactivity
- Human
- Clone
- WO2
- Applications
- WB, ELISA, FuncS
Product Property
- Purity
- >95% as determined by analysis by SDS-PAGE
- Concentration
- Please refer to the vial label for the specific concentration.
- Buffer
- PBS
- Preservative
- No preservatives
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Target
- Alternative Names
- APP; amyloid beta (A4) precursor protein; AAA; AD1; PN2; ABPP; APPI; CVAP; ABETA; PN-II; CTFgamma; amyloid beta A4 protein; preA4; protease nexin-II; peptidase nexin-II; beta-amyloid peptide; beta-amyloid peptide(1-40); beta-amyloid peptide(1-42); alzheimer disease amyloid protein; cerebral vascular amyloid peptide
- Gene ID
- 351
- UniProt ID
- P05067
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
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|---|---|---|---|
| TAB-228 | Anti-Human Abeta Recombinant Antibody (Solanezumab) | WB, FuncS, IF, Neut, ELISA, FC, IP | IgG1 - kappa |
| TAB-227 | Anti-Human Abeta Recombinant Antibody (Ponezumab) | WB, ELISA, IP, FC, FuncS, Neut, IF | IgG2 - kappa |
| TAB-253CQ-F(E) | Human Anti-APP Recombinant Antibody; Fab Fragment (TAB-253CQ-F(E)) | ELISA | Humanized Fab |
| TAB-0828CLV-F(E) | Human Anti-APP Recombinant Antibody; Fab Fragment (TAB-0828CLV-F(E)) | ELISA | Humanized Fab |
| TAB-0829CLV-F(E) | Human Anti-APP Recombinant Antibody; Fab Fragment (TAB-0829CLV-F(E)) | ELISA | Humanized Fab |
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