Mouse Anti-APP Recombinant Antibody (clone PFA2); Fab Fragment (CAT#: PFBC-010)

Recombinant Mouse Antibody (PFA2) Fab Fragment is specific to APP.

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  • Conjugation:

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Custom Production

We specialize in custom recombinant antibody production, offering seamless execution from provided sequences to high-quality antibody deliverables, ensuring optimal yield and purity.

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We require custom production
  • Published Data
  • Gene Expression
  • Datasheet
  • MSDS
  • COA

Figure 1 ELISA EC₅₀ and SPR K<sub>d</sub> values

Figure 1 ELISA EC₅₀ and SPR Kd values

Gardberg, A. S., Dice, L. T., Ou, S., Rich, R. L., Helmbrecht, E., Ko, J., ... & Dealwis, C. (2007). Molecular basis for passive immunotherapy of Alzheimer's disease. Proceedings of the National Academy of Sciences, 104(40), 15659-15664.

Figure 2 SPR results for A<em>β</em>(2–7), Grip1(110–115), Ror2(518–525), and pyroglutamic A<em>β</em>(3–8)

Figure 2 SPR results for Aβ(2–7), Grip1(110–115), Ror2(518–525), and pyroglutamic Aβ(3–8)

Gardberg, A. S., Dice, L. T., Ou, S., Rich, R. L., Helmbrecht, E., Ko, J., ... & Dealwis, C. (2007). Molecular basis for passive immunotherapy of Alzheimer's disease. Proceedings of the National Academy of Sciences, 104(40), 15659-15664.


Specifications

  • Immunogen
  • Human amyloid beta (A4) precursor protein
  • Host Species
  • Mouse
  • Derivation
  • Mouse
  • Type
  • Mouse IgG2a
  • Specificity
  • APP
  • Species Reactivity
  • Human
  • Clone
  • PFA2
  • Applications
  • ELISA

Product Property

  • Purity
  • >95% as determined by analysis by SDS-PAGE
  • Concentration
  • Please refer to the vial label for the specific concentration.
  • Buffer
  • PBS
  • Preservative
  • No preservatives
  • Storage
  • Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

  • Alternative Names
  • APP; amyloid beta (A4) precursor protein; AAA; AD1; PN2; ABPP; APPI; CVAP; ABETA; PN-II; CTFgamma; amyloid beta A4 protein; preA4; protease nexin-II; peptidase nexin-II; beta-amyloid peptide; beta-amyloid peptide(1-40); beta-amyloid peptide(1-42); alzheimer disease amyloid protein; cerebral vascular amyloid peptide

Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Downloads

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