Mouse Anti-APP Recombinant Antibody (clone PFA2); Fab Fragment (CAT#: PFBC-010)

Recombinant Mouse Antibody (PFA2) Fab Fragment is specific to APP.


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  • Published Data
  • Gene Expression
  • Datasheet
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  • COA

Figure 1 ELISA EC₅₀ and SPR K<sub>d</sub> values

Figure 1 ELISA EC₅₀ and SPR Kd values

Gardberg, A. S., Dice, L. T., Ou, S., Rich, R. L., Helmbrecht, E., Ko, J., ... & Dealwis, C. (2007). Molecular basis for passive immunotherapy of Alzheimer's disease. Proceedings of the National Academy of Sciences, 104(40), 15659-15664.

Figure 2 SPR results for A<em>β</em>(2–7), Grip1(110–115), Ror2(518–525), and pyroglutamic A<em>β</em>(3–8)

Figure 2 SPR results for Aβ(2–7), Grip1(110–115), Ror2(518–525), and pyroglutamic Aβ(3–8)

Gardberg, A. S., Dice, L. T., Ou, S., Rich, R. L., Helmbrecht, E., Ko, J., ... & Dealwis, C. (2007). Molecular basis for passive immunotherapy of Alzheimer's disease. Proceedings of the National Academy of Sciences, 104(40), 15659-15664.


Specifications

  • Immunogen
  • Human amyloid beta (A4) precursor protein
  • Host Species
  • Mouse
  • Derivation
  • Mouse
  • Type
  • Mouse IgG2a
  • Specificity
  • APP
  • Species Reactivity
  • Human
  • Clone
  • PFA2
  • Applications
  • ELISA

Product Property

  • Purity
  • >95% as determined by analysis by SDS-PAGE
  • Concentration
  • Please refer to the vial label for the specific concentration.
  • Buffer
  • PBS
  • Preservative
  • No preservatives
  • Storage
  • Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

  • Alternative Names
  • APP; amyloid beta (A4) precursor protein; AAA; AD1; PN2; ABPP; APPI; CVAP; ABETA; PN-II; CTFgamma; amyloid beta A4 protein; preA4; protease nexin-II; peptidase nexin-II; beta-amyloid peptide; beta-amyloid peptide(1-40); beta-amyloid peptide(1-42); alzheimer disease amyloid protein; cerebral vascular amyloid peptide

Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Downloads

Download resources about recombinant antibody development and antibody engineering to boost your research.

See other products for "Clone PFA2"

See other products for "APP"

Recombinant Antibody

CAT Product Name Application Type
MOB-1185z Mouse Anti-APP Recombinant Antibody (clone 25F3) WB, FC, ICC, IF, IHC Mouse IgG1
PABL-010 Mouse Anti-APP Recombinant Antibody (clone 12A11) WB, IF, FuncS Mouse IgG2a, κ
PABL-011 Mouse Anti-APP Recombinant Antibody (clone 3D6) WB, ELISA, FuncS Mouse IgG1
PABL-012 Human Anti-APP Recombinant Antibody (clone 9TL) WB, FuncS Human IgG2, κ
PABL-013 Mouse Anti-APP Recombinant Antibody (clone C705) WB, ELISA, FuncS Mouse IgG

Single-domain Antibody

Humanized Antibody

Chicken IgY Antibody

CAT Product Name Application Type
BRD-0685MZ Chicken Anti-APP Polyclonal IgY IHC Chicken antibody

ADCC Enhanced Antibody

CAT Product Name Application Type
AFC-TAB-225 Afuco™ Anti-APP ADCC Recombinant Antibody (Bapineuzumab), ADCC Enhanced FuncS, IF, Neut, ELISA, FC ADCC enhanced antibody
AFC-TAB-228 Afuco™ Anti-APP ADCC Recombinant Antibody (Solanezumab), ADCC Enhanced FuncS, IF, Neut, ELISA, FC ADCC enhanced antibody
AFC-TAB-229 Afuco™ Anti-APP ADCC Recombinant Antibody (Gantenerumab), ADCC Enhanced FuncS, IF, Neut, ELISA, FC, IP ADCC enhanced antibody
AFC-TAB-227 Afuco™ Anti-APP ADCC Recombinant Antibody (Ponezumab), ADCC Enhanced ELISA, IP, FC, FuncS, Neut ADCC enhanced antibody
AFC-TAB-226 Afuco™ Anti-APP ADCC Recombinant Antibody (Crenezumab), ADCC Enhanced IF, IP, Neut, FuncS, ELISA ADCC enhanced antibody

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For Research Use Only. Not For Clinical Use.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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