Hi-Affi™ Rabbit Anti-APP Recombinant Antibody (clone TH47DS) (CAT#: MOR-4539)
Recombinant Rabbit anti-APP monoclonal antibody for IHC-P, ELISA, excellent for producing superior results. Hi-Affi™ antibodies are developed from different sources, such as B cells of immunized animals, hybridoma, phage display library. The application of recombinant technology avoids the traditional ascitic fluid approach, which achieves the antibody generation in a humane way with much larger scale, greater specificity and sensitivity, and not susceptible to cell-line drift or lot-to-lot variation.
Specific Inquiry
Subcellular Location
Normal Tissue
RNA Expression
Figure 1 IF staining of human cell line U-2 OS
(Immunofluorescent staining of human cell line U-2 OS shows localization to the Golgi apparatus & vesicles.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/1462/if_selected.jpg
(Immunofluorescent staining of human cell line U-2 OS shows localization to the Golgi apparatus & vesicles.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/1462/if_selected.jpg
Figure 2 IF staining of human cell line A-431
(Immunofluorescent staining of human cell line A-431 shows localization to the Golgi apparatus.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/1462/60_E2_1_blue_red_green.jpg
(Immunofluorescent staining of human cell line A-431 shows localization to the Golgi apparatus.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/1462/60_E2_1_blue_red_green.jpg
Figure 3 IF staining of human cell line U-251 MG
(Immunofluorescent staining of human cell line U-251 MG shows localization to the Golgi apparatus.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/1462/61_E2_1_blue_red_green.jpg
(Immunofluorescent staining of human cell line U-251 MG shows localization to the Golgi apparatus.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/1462/61_E2_1_blue_red_green.jpg
Figure 4 Cerebral cortex
(Neuronal cells
Staining: Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/157/2073_B_7_5.jpg
(Neuronal cells
Staining: Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/157/2073_B_7_5.jpg
Figure 5 RNA cell line category: Low cell line specificity
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000142192-APP
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000142192-APP
Figure 5 RNA cell line category: Low cell line specificity
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000142192-APP
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000142192-APP
Specifications
- Immunogen
- APeptide corresponding to amino acids 707-713 of P05067.
- Host Species
- Rabbit
- Type
- Rabbit IgG
- Species Reactivity
- Human, Mouse
- Clone
- TH47DS
- Applications
- IHC-P, ELISA
- Conjugate
- Unconjugated
Product Property
- Purification
- Purified with Absolute Mag™ Protein A Agarose
- Purity
- >95% as determined by analysis by SDS-PAGE
- Format
- Liquid
- Buffer
- PBS
- Preservative
- 0.09% sodium azide
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Target
- Alternative Names
- Amyloid Beta (A4) Precursor Protein; Alzheimer Disease Amyloid Protein; Cerebral Vascular Amyloid Peptide; Peptidase Nexin-II; Protease Nexin-II; PN-II; PreA4; ABPP; APPI; CVAP; AD1; Beta-Amyloid Peptide(1-40); Beta-Amyloid Peptide(1-42); Beta-Amyloid Peptide; Alzheimer Disease; CTFgamma; ABETA; AAA; PN2; A4
- Gene ID
- 351
- UniProt ID
- P05067
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
See other products for "APP"
Single-domain Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NABG-016 | Recombinant Anti-Human APP VHH Single Domain Antibody | CA, IP, IF, FuncS | Llama VHH |
| PNBL-003 | Recombinant Anti-Human APP VHH Single Domain Antibody (G7) | WB, ELISA, FuncS | Llama VHH |
| PNBL-004 | Recombinant Anti-Human APP VHH Single Domain Antibody (PS2-8) | WB, ELISA, FuncS | Llama VHH |
| PNBL-070 | Recombinant Anti-APP VHH Single Domain Antibody (KW1) | ELISA, Neut, WB, Inhibition | Llama VHH |
| HPAB-1136-CN-VHH | Camelid Anti-APP Recombinant Antibody (HPAB-1136-CN-VHH) | WB, ELISA, IHC | Camelid VHH |
Human Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-0343CL-S(P) | Human Anti-APP Recombinant Antibody; scFv Fragment (TAB-0343CL-S(P)) | ELISA, FuncS, In vivo | Human scFv |
| TAB-0344CL-S(P) | Human Anti-APP Recombinant Antibody; scFv Fragment (TAB-0344CL-S(P)) | ELISA, FuncS, In vivo | Human scFv |
| TAB-0801CLV | Anti-Human APP Recombinant Antibody (3H3) | IHC, FuncS | Fully human antibody |
| TAB-0815CLV | Human Anti-APP Recombinant Antibody (TAB-0815CLV) | ELISA | Human IgG |
| TAB-0815CLV-S(P) | Human Anti-APP Recombinant Antibody; scFv Fragment (TAB-0815CLV-S(P)) | ELISA | Human scFv |
Chimeric Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-254CQ-S(P) | Mouse Anti-APP Recombinant Antibody; scFv Fragment (TAB-254CQ-S(P)) | ELISA | Mouse scFv |
| TAB-254CQ-F(E) | Human Anti-APP Recombinant Antibody; Fab Fragment (TAB-254CQ-F(E)) | ELISA | Chimeric (mouse/human) Fab |
| TAB-0789CLV | Human Anti-APP Recombinant Antibody (TAB-0789CLV) | IP | Chimeric (mouse/human) IgG |
| TAB-0789CLV-F(E) | Human Anti-APP Recombinant Antibody; Fab Fragment (TAB-0789CLV-F(E)) | ELISA | Chimeric (mouse/human) Fab |
| TAB-0789CLV-S(P) | Mouse Anti-APP Recombinant Antibody; scFv Fragment (TAB-0789CLV-S(P)) | ELISA | Mouse scFv |
Humanized Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-253CQ-F(E) | Human Anti-APP Recombinant Antibody; Fab Fragment (TAB-253CQ-F(E)) | ELISA | Humanized Fab |
| TAB-0828CLV-F(E) | Human Anti-APP Recombinant Antibody; Fab Fragment (TAB-0828CLV-F(E)) | ELISA | Humanized Fab |
| TAB-0829CLV-F(E) | Human Anti-APP Recombinant Antibody; Fab Fragment (TAB-0829CLV-F(E)) | ELISA | Humanized Fab |
| TAB-0830CLV-F(E) | Human Anti-APP Recombinant Antibody; Fab Fragment (TAB-0830CLV-F(E)) | ELISA | Humanized Fab |
| TAB-0831CLV-F(E) | Human Anti-APP Recombinant Antibody; Fab Fragment (TAB-0831CLV-F(E)) | ELISA | Humanized Fab |
Mouse Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-0808CLV-S(P) | Mouse Anti-APP Recombinant Antibody; scFv Fragment (TAB-0808CLV-S(P)) | ELISA | Mouse scFv |
| TAB-0827CLV-S(P) | Mouse Anti-APP Recombinant Antibody; scFv Fragment (TAB-0827CLV-S(P)) | ELISA | Mouse scFv |
| TAB-0838CLV-S(P) | Mouse Anti-Abeta protofibril Recombinant Antibody; scFv Fragment (TAB-0838CLV-S(P)) | ELISA | Mouse scFv |
| TAB-0839CLV-S(P) | Mouse Anti-Abeta protofibril Recombinant Antibody; scFv Fragment (TAB-0839CLV-S(P)) | ELISA | Mouse scFv |
| TAB-0840CLV-S(P) | Mouse Anti-APP Recombinant Antibody; scFv Fragment (TAB-0840CLV-S(P)) | ELISA | Mouse scFv |
Chicken IgY Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| BRD-0685MZ | Chicken Anti-APP Polyclonal IgY | IHC | Chicken antibody |
Rabbit Monoclonal Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PABX-014 | Hi-Affi™ Rabbit Anti-APP Recombinant Antibody (clone M204) | WB, ELISA, FuncS | Rabbit IgG |
| PABX-014-F (E) | Hi-Affi™ Rabbit Anti-APP Recombinant Antibody (clone M204); Fab Fragment | WB, ELISA, FuncS | Rabbit Fab |
| MOR-0220 | Hi-Affi™ Rabbit Anti-APP Recombinant Antibody (clone DS220AB) | ELISA, WB | Rabbit IgG |
| MOR-0082-FY | Rabbit Anti-APP Recombinant Antibody (clone AFY0053) | ICC, IHC-P, WB | Rabbit IgG |
Epitope-Specific Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| EPAF-0566CQ | Mouse Anti-APP Recombinant Antibody (clone 6E10) | ELISA | Mouse IgG |
| EPAF-0567CQ | Mouse Anti-APP Recombinant Antibody (clone 4G8) | ELISA, IHC | Mouse IgG2b |
| EPAF-0568CQ | Human Anti-APP Recombinant Antibody (clone HyL5) | ELISA, Inhib | Human IgM |
| EPAF-0569CQ | Mouse Anti-APP Recombinant Antibody (clone AB1-42) | IHC | Mouse IgG |
| EPAF-0570CQ | Human Anti-APP Recombinant Antibody (clone L11.3) | IHC, ELISA, Inhib | Human IgM |
Neuroscience Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NS-001CN | Human Anti-APP Recombinant Antibody (clone AS) | WB | Human IgG |
| NS-007CN | Mouse Anti-APP Recombinant Antibody (NS-007CN) | ELISA, FuncS | Mouse IgG1 |
| NS-001CN-F(E) | Human Anti-APP Recombinant Antibody (clone AS); Fab Fragment | WB | Human Fab |
| NS-007CN-F(E) | Mouse Anti-APP Recombinant Antibody; Fab Fragment (NS-007CN-F(E)) | ELISA | Mouse Fab |
| NS-001CN-S(P) | Human Anti-APP Recombinant Antibody (clone AS); scFv Fragment | WB | Human scFv |
Recombinant Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0116CQ | Mouse Anti-APP Recombinant Antibody (HPAB-0116CQ) | ELISA, WB, IP, FuncS | Mouse IgG1, κ |
| HPAB-0117CQ | Human Anti-APP Recombinant Antibody (HPAB-0117CQ) | ELISA, WB, IP, FuncS | Human IgG1, κ |
| HPAB-0118CQ | Human Anti-APP Recombinant Antibody (clone Fv1E4) | ELISA, Inhib | Human IgG |
| HPAB-0119CQ | Human Anti-APP Recombinant Antibody (clone h12A11v1) | ELISA, CFC, FuncS | Human IgG1 |
| HPAB-0120CQ | Human Anti-APP Recombinant Antibody (HPAB-0120CQ) | ELISA, IHC, FuncS | Human IgG1 |
Fab Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0116CQ-F(E) | Mouse Anti-APP Recombinant Antibody; Fab Fragment (HPAB-0116CQ-F(E)) | ELISA, WB, IP, FuncS | Mouse Fab |
| HPAB-0117CQ-F(E) | Human Anti-APP Recombinant Antibody; Fab Fragment (HPAB-0117CQ-F(E)) | ELISA, WB, IP, FuncS | Human Fab |
| HPAB-0118CQ-F(E) | Human Anti-APP Recombinant Antibody (clone Fv1E4); Fab Fragment | ELISA, Inhib | Human Fab |
| HPAB-0119CQ-F(E) | Human Anti-APP Recombinant Antibody (clone h12A11v1); Fab Fragment | ELISA, FuncS | Human Fab |
| HPAB-0120CQ-F(E) | Human Anti-APP Recombinant Antibody; Fab Fragment (HPAB-0120CQ-F(E)) | ELISA, IHC, FuncS | Human Fab |
ADCC Enhanced Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| AFC-TAB-225 | Afuco™ Anti-APP ADCC Recombinant Antibody (Bapineuzumab), ADCC Enhanced | FuncS, IF, Neut, ELISA, FC | ADCC enhanced antibody |
| AFC-TAB-228 | Afuco™ Anti-APP ADCC Recombinant Antibody (Solanezumab), ADCC Enhanced | FuncS, IF, Neut, ELISA, FC | ADCC enhanced antibody |
| AFC-TAB-229 | Afuco™ Anti-APP ADCC Recombinant Antibody (Gantenerumab), ADCC Enhanced | FuncS, IF, Neut, ELISA, FC, IP | ADCC enhanced antibody |
| AFC-TAB-227 | Afuco™ Anti-APP ADCC Recombinant Antibody (Ponezumab), ADCC Enhanced | ELISA, IP, FC, FuncS, Neut | ADCC enhanced antibody |
| AFC-TAB-226 | Afuco™ Anti-APP ADCC Recombinant Antibody (Crenezumab), ADCC Enhanced | IF, IP, Neut, FuncS, ELISA | ADCC enhanced antibody |
scFv Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0345-YJ-S(P) | Human Anti-APP Recombinant Antibody (clone B6); scFv Fragment | ELISA, Inhib, WB | Human scFv |
| HPAB-0346-YJ-S(P) | Human Anti-APP Recombinant Antibody (clone B7); scFv Fragment | ELISA, Inhib, WB | Human scFv |
| HPAB-0346-FY-S(P) | Mouse Anti-APP Recombinant Antibody (clone IBL-102); scFv Fragment | Cyt, WB, ELISA | Mouse scFv |
| HPAB-S0005-YC-S(P) | Human Anti-APP Recombinant Antibody (clone ch3D6); scFv Fragment | ELISA, FuncS | Human scFv |
| HPAB-1828-FY-F(E) | Mouse Anti-APP Recombinant Antibody (clone 2324); scFv Fragment | ELISA | Mouse scFv |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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