Anti-Human AXL Recombinant Antibody scFv Fragment (Humanized 11B7) (CAT#: TAB-1098CL-S(P))
The anti-AXL antibody targets AXL, and with the ADC form, the antibody can be used in the treatment of cancers, such as prostate cancer and breast cancer.
Specific Inquiry
Subcellular Location
Normal Tissue
RNA Expression
Figure 1 IF staining of human cell line U-251 MG
(Immunofluorescent staining of human cell line U-251 MG shows localization to plasma membrane, actin filaments & vesicles.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/75217/1899_C1_1_selected.jpg
(Immunofluorescent staining of human cell line U-251 MG shows localization to plasma membrane, actin filaments & vesicles.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/75217/1899_C1_1_selected.jpg
Figure 2 IHC staining of human thyroid gland
(Immunohistochemical staining of human thyroid gland shows strong cytoplasmic positivity in glandular cells.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/32501/ihc_selected.jpg
(Immunohistochemical staining of human thyroid gland shows strong cytoplasmic positivity in glandular cells.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/32501/ihc_selected.jpg
Figure 3 Skeletal muscle
(Myocytes Staining: High Intensity: Strong Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/37422/82809_B_1_6.jpg
(Myocytes Staining: High Intensity: Strong Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/37422/82809_B_1_6.jpg
Figure 4 Colon
(Glandular cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/37422/82809_A_8_3.jpg
(Glandular cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/37422/82809_A_8_3.jpg
Figure 5 Kidney
(Cells in glomeruli Staining: Low Intensity: Weak Quantity: 75%-25% Location: Cytoplasmic/ membranous Cells in tubules Staining: High Intensity: Strong Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/37422/82809_A_9_5.jpg
(Cells in glomeruli Staining: Low Intensity: Weak Quantity: 75%-25% Location: Cytoplasmic/ membranous Cells in tubules Staining: High Intensity: Strong Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/37422/82809_A_9_5.jpg
Figure 6 Testis
(Cells in seminiferous ducts Staining: High Intensity: Strong Quantity: 75%-25% Location: Cytoplasmic/ membranous Leydig cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/37422/82809_A_4_6.jpg
(Cells in seminiferous ducts Staining: High Intensity: Strong Quantity: 75%-25% Location: Cytoplasmic/ membranous Leydig cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/37422/82809_A_4_6.jpg
Figure 7 RNA cell line category: Cell line enhanced (fHDF/TERT166, U-251 MG)
(Cell lines ordered by descending RNA expression order)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000167601-AXL
(Cell lines ordered by descending RNA expression order)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000167601-AXL
Specifications
- Host Species
- Human
- Type
- Humanized antibody
- Specificity
- Human
- Clone
- Humanized 11B7
- Related Disease
- Breast cancer, Prostate cancer
Target
- Alternative Names
- AXL; AXL receptor tyrosine kinase; ARK; UFO; JTK11; Tyro7
- Gene ID
- 558
- UniProt ID
- P30530
Related Resources
EGFR Tyrosine Kinase Inhibitor Resistance
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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Mouse Antibody
Humanized Antibody
Chimeric Antibody
Rabbit Monoclonal Antibody
Fab Fragment Antibody
scFv Fragment Antibody
Recombinant Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-0138CL | Mouse Anti-Human AXL Recombinant Antibody (1613F12) | ELISA, IF, FC, Inhib, ICFC | |
| TAB-0336CL | Anti-Human AXL Recombinant Antibody | WB, FuncS, ELISA | |
| TAB-0188CL-S(P) | Mouse Anti-AXL Recombinant Antibody; scFv Fragment (TAB-0188CL-S(P)) | WB, FuncS, ELISA, FC | Mouse scFv |
| TAB-1087CL-S(P) | Mouse Anti-AXL Recombinant Antibody; scFv Fragment (TAB-1087CL-S(P)) | ELISA, FuncS | Mouse scFv |
| TAB-1088CL-S(P) | Mouse Anti-AXL Recombinant Antibody; scFv Fragment (TAB-1088CL-S(P)) | ELISA, FuncS | Mouse scFv |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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