Anti-Human BMP4 VHH Single Domain Antibody (TAB-0069CL-VHH) (CAT#: TAB-0069CL-VHH)
These single chain antibodies which can bind to an epitope located within the BMPR1 binding region of BMP4 can be used in the treatment of SMAD4 deficient cancer.
Specific Inquiry
Normal Tissue
RNA Expression
Figure 1 IHC staining of human smooth muscle
(Immunohistochemical staining of human smooth muscle shows strong cytoplasmic positivity in smooth muscle cells.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/66235/ihc_selected.jpg
(Immunohistochemical staining of human smooth muscle shows strong cytoplasmic positivity in smooth muscle cells.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/66235/ihc_selected.jpg
Figure 2 IHC staining of human duodenum
(Immunohistochemical staining of human duodenum shows distinct cytoplasmic and extra cellular positivity in glandular cells.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/6863/ihc_selected.jpg
(Immunohistochemical staining of human duodenum shows distinct cytoplasmic and extra cellular positivity in glandular cells.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/6863/ihc_selected.jpg
Figure 3 Colon
(Endothelial cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/66235/153903_A_7_3.jpg
(Endothelial cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/66235/153903_A_7_3.jpg
Figure 4 Smooth muscle
(Smooth muscle cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/66235/153903_B_6_7.jpg
(Smooth muscle cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/66235/153903_B_6_7.jpg
Figure 5 RNA cell line category: Cell line enhanced (CACO-2, CAPAN-2, Hep G2, OE19, SuSa)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000125378-BMP4
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000125378-BMP4
Specifications
- Immunogen
- Recombinant BMP4
- Host Species
- Llama
- Derivation
- Phage-display library (VHH library)
- Type
- Single domain antibody (VHH)
- Specificity
- Human
- Clone
- TAB-0069CL-VHH
- Related Disease
- SMAD4 deficient cancer
Target
- Alternative Names
- BMP4; bone morphogenetic protein 4; ZYME; BMP2B; OFC11; BMP2B1; MCOPS6; BMP-4
- Gene ID
- 652
- UniProt ID
- P12644
Related Resources
TGF-β Signaling Pathway
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
See other products for "BMP4"
Recombinant Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-2244z | Mouse Anti-BMP4 Recombinant Antibody (clone 18H6) | WB, ELISA, FC, ICC, IHC | Mouse IgG1 |
| MOB-1495MZ | Mouse Anti-BMP4 Recombinant Antibody (clone 20G5C5) | ELISA, ICC, WB | Mouse IgG1 |
| ZG-0339F | Mouse Anti-BMP4 Recombinant Antibody (ZG-0339F) | WB, ELISA | Mouse IgG |
| VS3-QX123 | Mouse Anti-BMP4 Recombinant Antibody (clone 1C-17) | WB, ICC, FC | Mouse IgG1 |
| VS4-WK50 | Rabbit Anti-BMP4 Recombinant Antibody (clone 19B7) | ELISA, WB, IF | Rabbit IgG |
Mouse Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-1272CL | Mouse Anti-BMP4 Recombinant Antibody (TAB-1272CL) | FuncS | Mouse IgG2b, κ |
| TAB-1273CL | Mouse Anti-BMP4 Recombinant Antibody (TAB-1273CL) | FuncS | Mouse IgG1, κ |
| TAB-1272CL-S(P) | Mouse Anti-BMP4 Recombinant Antibody; scFv Fragment (TAB-1272CL-S(P)) | FuncS | Mouse scFv |
| TAB-1272CL-F(E) | Mouse Anti-BMP4 Recombinant Antibody; Fab Fragment (TAB-1272CL-F(E)) | FuncS | Mouse Fab |
| TAB-1273CL-F(E) | Mouse Anti-BMP4 Recombinant Antibody; Fab Fragment (TAB-1273CL-F(E)) | FuncS | Mouse Fab |
Neutralizing Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-051CQ | Mouse Anti-BMP4 Recombinant Antibody (clone 3H2) | ELISA, Neut, WB | Mouse IgG2b, κ |
| NEUT-052CQ | Mouse Anti-BMP4 Recombinant Antibody (clone CBL815) | Neut, WB | Mouse IgG2b |
| NEUT-053CQ | Mouse Anti-BMP4 Recombinant Antibody (clone CBL816) | WB, Neut, ELISA | Mouse IgG2b |
| NEUT-054CQ | Mouse Anti-BMP4 Recombinant Antibody (clone CBL987) | ELISA, WB, IHC, Neut | Mouse IgG2b, κ |
| NEUT-055CQ | Rat Anti-BMP4 Recombinant Antibody (clone CBL387) | Neut | Rat IgG1 |
Rabbit Monoclonal Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-0367 | Hi-Affi™ Rabbit Anti-BMP4 Recombinant Antibody (clone DS367AB) | WB, IHC, ICC, IP, FC | Rabbit IgG |
Single-domain Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0355-YC-VHH | Recombinant Llama Anti-BMP4 Single Domain Antibody (HPAB-0355-YC-VHH) | FuncS, SPR, Activ | Llama VHH |
| HPAB-0356-YC-VHH | Recombinant Llama Anti-BMP4 Single Domain Antibody (HPAB-0356-YC-VHH) | Inhib, SPR | Llama VHH |
| HPAB-0357-YC-VHH | Recombinant Llama Anti-BMP4 Single Domain Antibody (HPAB-0357-YC-VHH) | Inhib, SPR | Llama VHH |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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