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Recombinant Anti-human BaX Intrabody [+36GFP] (CAT#: IAB-B001(G))

Recombinant anti-BaX intrabody in fusion with +36GFP works within cells to bind pro-apoptotic protein BaX, expressed in CHO cells. These intrabodies are useful drugs on their own as well as a means for identifying small compound drugs for degenerative diseases involving oxidative-stress-induced apoptosis.

Specific Inquiry
  • Size:
  • Conjugation:
  • Endotoxin:
  • Purity:
  • Formats:
  • Isotype Switching:
  • Fc Engineering:
  • Modalities:
  • Gene Expression
  • Datasheet
  • MSDS
  • COA
Normal Tissue
Figure 1 Cerebral cortex
Figure 1 Cerebral cortex
(Endothelial cells
Staining: Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/membranous
Glial cells
Staining: Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/membranous
Neuronal cells
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/4206/13374_B_7_5.jpg
Figure 2 Colon
Figure 2 Colon
(Endothelial cells
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous
Glandular cells
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/4206/13374_A_7_3.jpg
Figure 3 Liver
Figure 3 Liver
(Cholangiocytes
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/4206/13374_A_9_4.jpg
Figure 4 Kidney
Figure 4 Kidney
(Cells in glomeruli
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous
Cells in tubules
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/4206/13374_A_7_5.jpg
Figure 5 Testis
Figure 5 Testis
(Cells in seminiferous ducts
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous
Leydig cells
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/4206/13374_A_4_6.jpg
Figure 6 Lymph node
Figure 6 Lymph node
(Germinal center cells
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous
Non-germinal center cells
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/4206/13374_A_7_8.jpg
RNA Expression
Figure 7 RNA cell line category: Low cell line specificity
Figure 7 RNA cell line category: Low cell line specificity
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000087088-BAX

Specifications

  • Immunogen
  • human BCL2-associated X protein
  • Host Species
  • llama
  • Type
  • vhh-(+36GFP)
  • Cell Penetrating Peptide
  • +36 GFP
    GFP with a theoretical net charge of +36 (+36 GFP) penetrated several different mammalian cell lines at very low (nanomolar) concentrations. Cationic peptides and proteins have been observed to penetrate cells, and both natural and synthetic cell-penetrating peptides are widely used as delivery vehicles. However, whereas a covalent link between the cell-penetrating peptide and its cargo is typically required.
  • Species Reactivity
  • human
  • Applications
  • Formats of immunological tests: Protein fragment complementation; Neutralization; Functional studies

Product Property

  • Purity
  • >95% as determined by Analysis by RP-HPLC & analysis by SDS-PAGE
  • Storage
  • Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

  • Alternative Names
  • BAX; BCL2-associated X protein; BCL2L4; apoptosis regulator BAX; bcl2-L-4; Baxdelta2G9; Baxdelta2omega; Baxdelta2G9omega; bcl-2-like protein 4; BCL2-associated X protein omega

Related Resources

  • Related Diseases
  • Related Signaling Pathways

Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Downloads

Download resources about recombinant antibody development and antibody engineering to boost your research.

See other products for "BAX"

Select a product category from the dropdown menu below to view related products.
Please select product type
Single Domain Antibody Products Intrabody Products Fab Antibody Products Neutralizing Antibody Products Rabbit Monoclonal Antibody Products ScFv Antibody Products IgG Antibody Products Antibody Magnetic Beads Non-Human Primate (NHP) Antibody Products
CAT Product Name Application Type
NABL-074 Recombinant Anti-human BAX VHH Single Domain Antibody WB, ELISA, IP, FuncS Llama VHH
TAB-0056CL-VHH Llama Anti-BAX Recombinant Antibody (TAB-0056CL-VHH) ELISA, FuncS, Apop, BI Llama VHH
TAB-0057CL-VHH Llama Anti-BAX Recombinant Antibody (TAB-0057CL-VHH) ELISA, FuncS, Apop, BI Llama VHH
TAB-0058CL-VHH Llama Anti-BAX Recombinant Antibody (TAB-0058CL-VHH) ELISA, FuncS, Apop, BI Llama VHH
TAB-0059CL-VHH Llama Anti-BAX Recombinant Antibody (TAB-0059CL-VHH) ELISA, FuncS, Apop, BI Llama VHH

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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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