Recombinant Anti-human BaX Intrabody [+36GFP]
CAT#: IAB-B001(G)
Recombinant anti-BaX intrabody in fusion with +36GFP works within cells to bind pro-apoptotic protein BaX, expressed in CHO cells. These intrabodies are useful drugs on their own as well as a means for identifying small compound drugs for degenerative diseases involving oxidative-stress-induced apoptosis.
Gene Expression
Normal Tissue
Figure 1 Cerebral cortex
Endothelial cells
Staining: Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/membranous
Glial cells
Staining: Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/membranous
Neuronal cells
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/4206/13374_B_7_5.jpg
Normal Tissue
Figure 2 Colon
Endothelial cells
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous
Glandular cells
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/4206/13374_A_7_3.jpg
Normal Tissue
Figure 3 Liver
Cholangiocytes
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/4206/13374_A_9_4.jpg
Normal Tissue
Figure 4 Kidney
Cells in glomeruli
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous
Cells in tubules
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/4206/13374_A_7_5.jpg
Normal Tissue
Figure 5 Testis
Cells in seminiferous ducts
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous
Leydig cells
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/4206/13374_A_4_6.jpg
Normal Tissue
Figure 6 Lymph node
Germinal center cells
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous
Non-germinal center cells
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/4206/13374_A_7_8.jpg
RNA Expression
Figure 7 RNA cell line category: Low cell line specificity
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000087088-BAX
❮
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Specifications
- Immunogen
- human BCL2-associated X protein
- Host Species
- llama
- Type
- vhh-(+36GFP)
- Cell Penetrating Peptide
- +36 GFP
GFP with a theoretical net charge of +36 (+36 GFP) penetrated several different mammalian cell lines at very low (nanomolar) concentrations. Cationic peptides and proteins have been observed to penetrate cells, and both natural and synthetic cell-penetrating peptides are widely used as delivery vehicles. However, whereas a covalent link between the cell-penetrating peptide and its cargo is typically required.
- Species Reactivity
- human
- Applications
- Formats of immunological tests: Protein fragment complementation; Neutralization; Functional studies
Product Property
- Purity
- >95% as determined by Analysis by RP-HPLC & analysis by SDS-PAGE
- Storage
- Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Target
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Related Diseases
Breast Cancer
Endometrial Cancer
Gastric Cancer
Prostate Cancer
Throid Cancer
AGE-RAGE Signaling Pathway in Diabetic Complications
Amyotrophic Lateral Sclerosis
Related Signaling Pathways
p53 Signaling Pathway
Downloadable Resources
Download resources about recombinant antibody development and antibody engineering to boost your research.
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
See other products for "BAX"
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-101-F(E) | Recombinant Anti-human BAX Antibody Fab Fragment | IP, FuncS | Fab |
| MHH-101-F(E) | Recombinant Human Anti-human BAX Antibody Fab Fragment | ELISA, WB, FC, FuncS | Fab |
| PFBC-014 | Mouse Anti-BAX Recombinant Antibody (clone 6A7); Fab Fragment | WB, FuncS | Mouse IgG |
| PFBC-255 | Rat Anti-BAX Recombinant Antibody (clone 3C10); Fab Fragment | ELISA, WB, Inhib | Rat Fab |
| HPAB-2961LY-F(E) | Human Anti-BAX Recombinant Antibody; Fab Fragment (HPAB-2961LY-F(E)) | ELISA, Inhib | Human Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-101-S(P) | Recombinant Anti-human BAX Antibody scFv Fragment | ELISA, IF, FuncS | scFv |
| MHH-101-S(P) | Recombinant Human Anti-human BAX Antibody scFv Fragment | WB, Neut, FuncS | scFv |
| PSBC-014 | Mouse Anti-BAX Recombinant Antibody (clone 6A7); scFv Fragment | WB, FuncS | Mouse scFv |
| PSBC-255 | Rat Anti-BAX Recombinant Antibody (clone 3C10); scFv Fragment | ELISA, WB, Inhib | Rat scFv |
| HPAB-2961LY-S(P) | Human Anti-BAX Recombinant Antibody; scFv Fragment (HPAB-2961LY-S(P)) | ELISA, Inhib | Human scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| IAB-B001(A) | Recombinant Anti-human BaX Intrabody [(D-Arg)9] | ELISA, ICC, FuncS | vhh-(D-Arg)9 |
| IAB-B001(T) | Recombinant Anti-human BaX Intrabody [Tat] | WB, Neut, FuncS | vhh-Tat |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MHH-101 | Recombinant Human Anti-human BAX Antibody | ELISA, IF, FuncS | IgG |
| HPAB-2961LY | Human Anti-BAX Recombinant Antibody (HPAB-2961LY) | ELISA, Inhib | Human IgG |
| HPAB-2962LY | Human Anti-BAX Recombinant Antibody (HPAB-2962LY) | Inhib, ELISA | Human IgG |
| HPAB-2963LY | Human Anti-BAX Recombinant Antibody (HPAB-2963LY) | Inhib, ELISA | Human IgG |
| HPAB-2964LY | Human Anti-BAX Recombinant Antibody (HPAB-2964LY) | Block, ELISA, WB, FuncS | Human IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-0056CL-VHH | Llama Anti-BAX Recombinant Antibody (TAB-0056CL-VHH) | ELISA, FuncS, Apop, BI | Llama VHH |
| TAB-0057CL-VHH | Llama Anti-BAX Recombinant Antibody (TAB-0057CL-VHH) | ELISA, FuncS, Apop, BI | Llama VHH |
| TAB-0058CL-VHH | Llama Anti-BAX Recombinant Antibody (TAB-0058CL-VHH) | ELISA, FuncS, Apop, BI | Llama VHH |
| TAB-0059CL-VHH | Llama Anti-BAX Recombinant Antibody (TAB-0059CL-VHH) | ELISA, FuncS, Apop, BI | Llama VHH |
| TAB-0060CL-VHH | Llama Anti-BAX Recombinant Antibody (TAB-0060CL-VHH) | ELISA, FuncS, Apop, BI | Llama VHH |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-038CQ | Mouse Anti-BAX Recombinant Antibody (clone 2D2) | WB, IP, FC, IHC, Neut | Mouse IgG1, κ |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-0328 | Hi-Affi™ Rabbit Anti-BAX Recombinant Antibody (clone DS328AB) | IHC-P | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0724-YC93 | AbPlus™ Anti-Bax Magnetic Beads (VS-0724-YC93) | IP, Protein Purification |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-1024-XY47 | Mouse Anti-NHP BAX Recombinant Antibody (clone 2D2) | WB, IHC | Mouse IgG1 |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0325-XY225 | Anti-BAX Immunohistochemistry Kit | IHC | |
| VS-0525-XY699 | Anti-Mouse BAX Immunohistochemistry Kit | IHC | |
| VS-0525-XY698 | Anti-Human BAX Immunohistochemistry Kit | IHC |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS13-YC89 | CytoStream™ Rabbit Anti-BAX Recombinant Antibody (VS13-YC89) | WB, IF, FC, IP | Rabbit IgG |
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