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    Recombinant Anti-human BaX Intrabody [+36GFP] (CAT#: IAB-B001(G))

    Recombinant anti-BaX intrabody in fusion with +36GFP works within cells to bind pro-apoptotic protein BaX, expressed in CHO cells. These intrabodies are useful drugs on their own as well as a means for identifying small compound drugs for degenerative diseases involving oxidative-stress-induced apoptosis.

    Specific Inquiry
    • Size:

    • Conjugation:

    • Endotoxin:

    • Purity:

    • Formats:

    • Isotype Switching:

    • Fc Engineering:

    • Modalities:

    Custom Production

    We specialize in custom recombinant antibody production, offering seamless execution from provided sequences to high-quality antibody deliverables, ensuring optimal yield and purity.

    Sequences:
    Isotype :
    Purity :
    Endotoxin :
    Quantity :
    Conjugation :
    Fc Engineering :
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    Other Requirements:
    We require custom production
    • Gene Expression
    • Datasheet
    • MSDS
    • COA
    Normal Tissue
    Figure 1 Cerebral cortex
    Figure 1 Cerebral cortex
    (Endothelial cells
    Staining: Medium
    Intensity: Moderate
    Quantity: 75%-25%
    Location: Cytoplasmic/membranous
    Glial cells
    Staining: Medium
    Intensity: Moderate
    Quantity: 75%-25%
    Location: Cytoplasmic/membranous
    Neuronal cells
    Staining: High
    Intensity: Strong
    Quantity:>75%
    Location: Cytoplasmic/membranous)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/4206/13374_B_7_5.jpg
    Figure 2 Colon
    Figure 2 Colon
    (Endothelial cells
    Staining: Medium
    Intensity: Moderate
    Quantity:>75%
    Location: Cytoplasmic/membranous
    Glandular cells
    Staining: High
    Intensity: Strong
    Quantity:>75%
    Location: Cytoplasmic/membranous)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/4206/13374_A_7_3.jpg
    Figure 3 Liver
    Figure 3 Liver
    (Cholangiocytes
    Staining: Medium
    Intensity: Moderate
    Quantity:>75%
    Location: Cytoplasmic/membranous)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/4206/13374_A_9_4.jpg
    Figure 4 Kidney
    Figure 4 Kidney
    (Cells in glomeruli
    Staining: Medium
    Intensity: Moderate
    Quantity:>75%
    Location: Cytoplasmic/membranous
    Cells in tubules
    Staining: High
    Intensity: Strong
    Quantity:>75%
    Location: Cytoplasmic/membranous)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/4206/13374_A_7_5.jpg
    Figure 5 Testis
    Figure 5 Testis
    (Cells in seminiferous ducts
    Staining: High
    Intensity: Strong
    Quantity:>75%
    Location: Cytoplasmic/membranous
    Leydig cells
    Staining: High
    Intensity: Strong
    Quantity:>75%
    Location: Cytoplasmic/membranous)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/4206/13374_A_4_6.jpg
    Figure 6 Lymph node
    Figure 6 Lymph node
    (Germinal center cells
    Staining: Medium
    Intensity: Moderate
    Quantity:>75%
    Location: Cytoplasmic/membranous
    Non-germinal center cells
    Staining: Medium
    Intensity: Moderate
    Quantity:>75%
    Location: Cytoplasmic/membranous)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/4206/13374_A_7_8.jpg
    RNA Expression
    Figure 7 RNA cell line category: Low cell line specificity
    Figure 7 RNA cell line category: Low cell line specificity
    (Cell lines ordered by descending RNA expression order.)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000087088-BAX

    Specifications

    • Immunogen
    • human BCL2-associated X protein
    • Host Species
    • llama
    • Type
    • vhh-(+36GFP)
    • Cell Penetrating Peptide
    • +36 GFP
      GFP with a theoretical net charge of +36 (+36 GFP) penetrated several different mammalian cell lines at very low (nanomolar) concentrations. Cationic peptides and proteins have been observed to penetrate cells, and both natural and synthetic cell-penetrating peptides are widely used as delivery vehicles. However, whereas a covalent link between the cell-penetrating peptide and its cargo is typically required.
    • Species Reactivity
    • human
    • Applications
    • Formats of immunological tests: Protein fragment complementation; Neutralization; Functional studies

    Product Property

    • Purity
    • >95% as determined by Analysis by RP-HPLC & analysis by SDS-PAGE
    • Storage
    • Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

    Target

    • Alternative Names
    • BAX; BCL2-associated X protein; BCL2L4; apoptosis regulator BAX; bcl2-L-4; Baxdelta2G9; Baxdelta2omega; Baxdelta2G9omega; bcl-2-like protein 4; BCL2-associated X protein omega

    Related Resources

    • Related Diseases
    • Related Signaling Pathways

    Product Notes

    This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

    • Increased sensitivity
    • Confirmed specificity
    • High repeatability
    • Excellent batch-to-batch consistency
    • Sustainable supply
    • Animal-free production

    See more details about Hi-Affi™ recombinant antibody benefits.

    Downloads

    Download resources about recombinant antibody development and antibody engineering to boost your research.

    See other products for "BAX"

    Select a product category from the dropdown menu below to view related products.
    Please select product type
    ScFv Antibody Products Intrabody Products Fab Antibody Products Single Domain Antibody Products Neutralizing Antibody Products Rabbit Monoclonal Antibody Products IgG Antibody Products Antibody Magnetic Beads Non-Human Primate (NHP) Antibody Products IHC Kit and Antibody Products: Precision Tools for Immunohistochemistry Flow Cytometry (FC) related Reagents and Kits: Empowering Cell Function Research
    CAT Product Name Application Type
    MOB-101-S(P) Recombinant Anti-human BAX Antibody scFv Fragment ELISA, IF, FuncS scFv
    MHH-101-S(P) Recombinant Human Anti-human BAX Antibody scFv Fragment WB, Neut, FuncS scFv
    PSBC-014 Mouse Anti-BAX Recombinant Antibody (clone 6A7); scFv Fragment WB, FuncS Mouse scFv
    PSBC-255 Rat Anti-BAX Recombinant Antibody (clone 3C10); scFv Fragment ELISA, WB, Inhib Rat scFv
    HPAB-2961LY-S(P) Human Anti-BAX Recombinant Antibody; scFv Fragment (HPAB-2961LY-S(P)) ELISA, Inhib Human scFv

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    For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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