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Recombinant Anti-human BaX Intrabody [+36GFP] (CAT#: IAB-B001(G))

Recombinant anti-BaX intrabody in fusion with +36GFP works within cells to bind pro-apoptotic protein BaX, expressed in CHO cells. These intrabodies are useful drugs on their own as well as a means for identifying small compound drugs for degenerative diseases involving oxidative-stress-induced apoptosis.


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Specific Inquiry
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  • Purity:
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  • Gene Expression
  • Datasheet
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Normal Tissue
Figure 1 Cerebral cortex
Figure 1 Cerebral cortex
(Endothelial cells
Staining: Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/membranous
Glial cells
Staining: Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/membranous
Neuronal cells
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/4206/13374_B_7_5.jpg
Figure 2 Colon
Figure 2 Colon
(Endothelial cells
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous
Glandular cells
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/4206/13374_A_7_3.jpg
Figure 3 Liver
Figure 3 Liver
(Cholangiocytes
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/4206/13374_A_9_4.jpg
Figure 4 Kidney
Figure 4 Kidney
(Cells in glomeruli
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous
Cells in tubules
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/4206/13374_A_7_5.jpg
Figure 5 Testis
Figure 5 Testis
(Cells in seminiferous ducts
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous
Leydig cells
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/4206/13374_A_4_6.jpg
Figure 6 Lymph node
Figure 6 Lymph node
(Germinal center cells
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous
Non-germinal center cells
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/4206/13374_A_7_8.jpg
RNA Expression
Figure 7 RNA cell line category: Low cell line specificity
Figure 7 RNA cell line category: Low cell line specificity
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000087088-BAX

Specifications

  • Immunogen
  • human BCL2-associated X protein
  • Host Species
  • llama
  • Type
  • vhh-(+36GFP)
  • Cell Penetrating Peptide
  • +36 GFP
    GFP with a theoretical net charge of +36 (+36 GFP) penetrated several different mammalian cell lines at very low (nanomolar) concentrations. Cationic peptides and proteins have been observed to penetrate cells, and both natural and synthetic cell-penetrating peptides are widely used as delivery vehicles. However, whereas a covalent link between the cell-penetrating peptide and its cargo is typically required.
  • Species Reactivity
  • human
  • Applications
  • Formats of immunological tests: Protein fragment complementation; Neutralization; Functional studies

Product Property

  • Purity
  • >95% as determined by Analysis by RP-HPLC & analysis by SDS-PAGE
  • Storage
  • Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

  • Alternative Names
  • BAX; BCL2-associated X protein; BCL2L4; apoptosis regulator BAX; bcl2-L-4; Baxdelta2G9; Baxdelta2omega; Baxdelta2G9omega; bcl-2-like protein 4; BCL2-associated X protein omega

Related Resources

  • Related Diseases
  • Related Signaling Pathways

Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Downloads

Download resources about recombinant antibody development and antibody engineering to boost your research.

See other products for "BAX"

Recombinant Antibody

CAT Product Name Application Type
MOB-101 Recombinant Anti-human BAX Antibody ELISA, WB, IF, FuncS IgG
MOB-0900MZ Mouse Anti-BAX Recombinant Antibody (clone 6A7) IHC-P Mouse IgG1
MRO-0155-CN Rabbit Anti-BAX Recombinant Antibody (clone CBACN-060) WB, IHC, IP, FC Rabbit IgG
MRO-0156-CN Mouse Anti-BAX Recombinant Antibody (clone 3-D2) WB, IF, IHC, FC Mouse IgA
ZG-0044J Mouse Anti-BAX Recombinant Antibody (clone 1C1) WB, IHC-P, IF Mouse IgG

scFv Fragment Antibody

CAT Product Name Application Type
MOB-101-S(P) Recombinant Anti-human BAX Antibody scFv Fragment ELISA, IF, FuncS scFv
MHH-101-S(P) Recombinant Human Anti-human BAX Antibody scFv Fragment WB, Neut, FuncS scFv
PSBC-014 Mouse Anti-BAX Recombinant Antibody (clone 6A7); scFv Fragment WB, FuncS Mouse scFv
PSBC-255 Rat Anti-BAX Recombinant Antibody (clone 3C10); scFv Fragment ELISA, WB, Inhib Rat scFv
HPAB-2961LY-S(P) Human Anti-BAX Recombinant Antibody; scFv Fragment (HPAB-2961LY-S(P)) ELISA, Inhib Human scFv

Intrabody

CAT Product Name Application Type
IAB-B001(A) Recombinant Anti-human BaX Intrabody [(D-Arg)9] ELISA, ICC, FuncS vhh-(D-Arg)9
IAB-B001(T) Recombinant Anti-human BaX Intrabody [Tat] WB, Neut, FuncS vhh-Tat

Single-domain Antibody

CAT Product Name Application Type
TAB-0056CL-VHH Llama Anti-BAX Recombinant Antibody (TAB-0056CL-VHH) ELISA, FuncS, Apop, BI Llama VHH
TAB-0057CL-VHH Llama Anti-BAX Recombinant Antibody (TAB-0057CL-VHH) ELISA, FuncS, Apop, BI Llama VHH
TAB-0058CL-VHH Llama Anti-BAX Recombinant Antibody (TAB-0058CL-VHH) ELISA, FuncS, Apop, BI Llama VHH
TAB-0059CL-VHH Llama Anti-BAX Recombinant Antibody (TAB-0059CL-VHH) ELISA, FuncS, Apop, BI Llama VHH
TAB-0060CL-VHH Llama Anti-BAX Recombinant Antibody (TAB-0060CL-VHH) ELISA, FuncS, Apop, BI Llama VHH

Neutralizing Antibody

CAT Product Name Application Type
NEUT-038CQ Mouse Anti-BAX Recombinant Antibody (clone 2D2) WB, IP, FC, IHC, Neut Mouse IgG1, κ

Rabbit Monoclonal Antibody

CAT Product Name Application Type
MOR-0328 Hi-Affi™ Rabbit Anti-BAX Recombinant Antibody (clone DS328AB) IHC-P Rabbit IgG

Fab Fragment Antibody

CAT Product Name Application Type
PFBC-255 Rat Anti-BAX Recombinant Antibody (clone 3C10); Fab Fragment ELISA, WB, Inhib Rat Fab
HPAB-2961LY-F(E) Human Anti-BAX Recombinant Antibody; Fab Fragment (HPAB-2961LY-F(E)) ELISA, Inhib Human Fab
HPAB-2962LY-F(E) Human Anti-BAX Recombinant Antibody; Fab Fragment (HPAB-2962LY-F(E)) ELISA, Inhib Human Fab
HPAB-2963LY-F(E) Human Anti-BAX Recombinant Antibody; Fab Fragment (HPAB-2963LY-F(E)) ELISA, Inhib Human Fab
HPAB-2964LY-F(E) Human Anti-BAX Recombinant Antibody; Fab Fragment (HPAB-2964LY-F(E)) ELISA, Inhib Human Fab

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For Research Use Only. Not For Clinical Use.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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