Recombinant Anti-human BaX Intrabody [(D-Arg)9]
CAT#: IAB-B001(A)
Recombinant anti-BaX intrabody linked to (D-Arg)9 works within cells to bind pro-apoptotic protein BaX, expressed in CHO cells. These intrabodies are useful drugs on their own as well as a means for identifying small compound drugs for degenerative diseases involving oxidative-stress-induced apoptosis.
Gene Expression
Normal Tissue
Figure 1 Cerebral cortex
Endothelial cells
Staining: Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/membranous
Glial cells
Staining: Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/membranous
Neuronal cells
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/4206/13374_B_7_5.jpg
Normal Tissue
Figure 2 Colon
Endothelial cells
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous
Glandular cells
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/4206/13374_A_7_3.jpg
Normal Tissue
Figure 3 Liver
Cholangiocytes
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/4206/13374_A_9_4.jpg
Normal Tissue
Figure 4 Kidney
Cells in glomeruli
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous
Cells in tubules
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/4206/13374_A_7_5.jpg
Normal Tissue
Figure 5 Testis
Cells in seminiferous ducts
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous
Leydig cells
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/4206/13374_A_4_6.jpg
Normal Tissue
Figure 6 Lymph node
Germinal center cells
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous
Non-germinal center cells
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/4206/13374_A_7_8.jpg
RNA Expression
Figure 7 RNA cell line category: Low cell line specificity
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000087088-BAX
❮
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Specifications
- Immunogen
- human BCL2-associated X protein
- Host Species
- llama
- Type
- vhh-(D-Arg)9
- Cell Penetrating Peptide
- (D-Arg)9
It has been proven that polyarginine peptides composed of nine arginine amino acids (Arg-9) are able to translocate across cells very efficiently. This raises the question if molecular dynamics simulations would show a similar pathway for this highly hydrophilic and charged peptide as predicted for the Tat peptide. The simplicity of Arg-9 over other CPPs also helps isolate the role of the Arg sidechain on the translocation without the effect of other sidechains. Therefore, in this work we study computationally the translocation of Arg-9 through a lipid bilayer and show that the translocation mechanism is the same as for the Tat peptide.
- Species Reactivity
- human
- Applications
- Formats of immunological tests: Enzyme-linked Immunosorbent Assay; Immunocytochemistry; Functional studies
Product Property
- Purity
- >95%, by SDS-PAGE with Coomassie Brilliant Blue staining
- Storage
- Short term: store at 4°C (over 6 months), long term: -20°C or -80°C.
Target
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Related Diseases
Breast Cancer
Endometrial Cancer
Gastric Cancer
Prostate Cancer
Throid Cancer
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Amyotrophic Lateral Sclerosis
Related Signaling Pathways
p53 Signaling Pathway
Downloadable Resources
Download resources about recombinant antibody development and antibody engineering to boost your research.
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
See other products for "BAX"
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-101-F(E) | Recombinant Anti-human BAX Antibody Fab Fragment | IP, FuncS | Fab |
| PFBC-014 | Mouse Anti-BAX Recombinant Antibody (clone 6A7); Fab Fragment | WB, FuncS | Mouse IgG |
| PFBC-255 | Rat Anti-BAX Recombinant Antibody (clone 3C10); Fab Fragment | ELISA, WB, Inhib | Rat Fab |
| HPAB-2961LY-F(E) | Human Anti-BAX Recombinant Antibody; Fab Fragment (HPAB-2961LY-F(E)) | ELISA, Inhib | Human Fab |
| HPAB-2962LY-F(E) | Human Anti-BAX Recombinant Antibody; Fab Fragment (HPAB-2962LY-F(E)) | ELISA, Inhib | Human Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| IAB-B001(G) | Recombinant Anti-human BaX Intrabody [+36GFP] | PCA, Neut, FuncS | vhh-(+36GFP) |
| IAB-B001(T) | Recombinant Anti-human BaX Intrabody [Tat] | WB, Neut, FuncS | vhh-Tat |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PSBC-014 | Mouse Anti-BAX Recombinant Antibody (clone 6A7); scFv Fragment | WB, FuncS | Mouse scFv |
| HPAB-2961LY-S(P) | Human Anti-BAX Recombinant Antibody; scFv Fragment (HPAB-2961LY-S(P)) | ELISA, Inhib | Human scFv |
| HPAB-2962LY-S(P) | Human Anti-BAX Recombinant Antibody; scFv Fragment (HPAB-2962LY-S(P)) | ELISA, Inhib | Human scFv |
| HPAB-2963LY-S(P) | Human Anti-BAX Recombinant Antibody; scFv Fragment (HPAB-2963LY-S(P)) | ELISA, Inhib | Human scFv |
| HPAB-2964LY-S(P) | Human Anti-BAX Recombinant Antibody; scFv Fragment (HPAB-2964LY-S(P)) | ELISA, Inhib | Human scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-0056CL-VHH | Llama Anti-BAX Recombinant Antibody (TAB-0056CL-VHH) | ELISA, FuncS, Apop, BI | Llama VHH |
| TAB-0057CL-VHH | Llama Anti-BAX Recombinant Antibody (TAB-0057CL-VHH) | ELISA, FuncS, Apop, BI | Llama VHH |
| TAB-0058CL-VHH | Llama Anti-BAX Recombinant Antibody (TAB-0058CL-VHH) | ELISA, FuncS, Apop, BI | Llama VHH |
| TAB-0059CL-VHH | Llama Anti-BAX Recombinant Antibody (TAB-0059CL-VHH) | ELISA, FuncS, Apop, BI | Llama VHH |
| TAB-0060CL-VHH | Llama Anti-BAX Recombinant Antibody (TAB-0060CL-VHH) | ELISA, FuncS, Apop, BI | Llama VHH |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-038CQ | Mouse Anti-BAX Recombinant Antibody (clone 2D2) | WB, IP, FC, IHC, Neut | Mouse IgG1, κ |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-0328 | Hi-Affi™ Rabbit Anti-BAX Recombinant Antibody (clone DS328AB) | IHC-P | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MRO-0155-CN | Rabbit Anti-BAX Recombinant Antibody (clone CBACN-060) | WB, IHC, IP, FC | Rabbit IgG |
| MRO-0156-CN | Mouse Anti-BAX Recombinant Antibody (clone 3-D2) | WB, IF, IHC, FC | Mouse IgA |
| HPAB-2973LY | Human Anti-BAX Recombinant Antibody (HPAB-2973LY) | Inhib, ELISA | Human IgG |
| HPAB-2974LY | Human Anti-BAX Recombinant Antibody (HPAB-2974LY) | ELISA, Inhib | Human IgG |
| VS3-FY138 | Recombinant Mouse Anti-BAX Antibody (clone 2D8H2) | ELISA, IHC, FC | Mouse IgG2b |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0724-YC93 | AbPlus™ Anti-Bax Magnetic Beads (VS-0724-YC93) | IP, Protein Purification |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-1024-XY47 | Mouse Anti-NHP BAX Recombinant Antibody (clone 2D2) | WB, IHC | Mouse IgG1 |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0325-XY225 | Anti-BAX Immunohistochemistry Kit | IHC | |
| VS-0525-XY699 | Anti-Mouse BAX Immunohistochemistry Kit | IHC | |
| VS-0525-XY698 | Anti-Human BAX Immunohistochemistry Kit | IHC |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS13-YC89 | CytoStream™ Rabbit Anti-BAX Recombinant Antibody (VS13-YC89) | WB, IF, FC, IP | Rabbit IgG |
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