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    Anti-Human C16orf54 Recombinant Antibody (R29-67-4A) (CAT#: TAB-1324CL)

    This antibody can specifically bind to C16orf54, which can be used in the treatment of CLL and other hematologic cancers, including acute lymphocytic leukemia (ALL), acute myeloid leukemia (AML), chronic myeloid leukemia (CML), lymphoma, including Hodgkin and non-Hodgkin lymphoma, multiple myeloma, as well as solid tumors such as breast cancer and pancreatic cancer, and metastases of any of these cancers.

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    Custom Production

    We specialize in custom recombinant antibody production, offering seamless execution from provided sequences to high-quality antibody deliverables, ensuring optimal yield and purity.

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    We require custom production
    • Published Data
    • Gene Expression
    • Datasheet
    • MSDS
    • COA
    FuncS

    Figure 1 The inhibition of in vivo tumor growth in an acute myeloid leukemia xenograft.

    Figure 1 The inhibition of in vivo tumor growth in an acute myeloid leukemia xenograft.

    Acute myeloid leukemia cell line KG-1 was used as a therapeutic xenograft efficacy model, which expresses C16rf54 on the cell surface. Tumor volumes at which treatment was initiated were 92mm³. Anti C16orf54 monoclonal antibodies 7-1 C and 67-7A induced a statistically significant tumor growth inhibition of 69% (p=0.0078) and 70 % (p=0.0068), respectively. Anti C16orf54 monoclonal antibodies 67-4A and 7-2A did not induce any statistically significant tumor growth inhibition. HB121 was used as an IgG isotype negative control antibody.

    ELISA

    Figure 2 EC50 ELISA for the anti-huC16orf54 monoclonal antibodies R29-7-2A, R29-7-1 C, R29-67-4A, and R29-67-7A.

    Figure 2 EC50 ELISA for the anti-huC16orf54 monoclonal antibodies R29-7-2A, R29-7-1 C, R29-67-4A, and R29-67-7A.

    An isotype control, R22-4-26, is also shown.


    Specifications

    • Immunogen
    • Human C16orf54 (huC16orf54) expressing sarcoma cells
    • Host Species
    • Mouse
    • Specificity
    • Human
    • Species Reactivity
    • Cyno C16orf54
    • Clone
    • R29-67-4A
    • Applications
    • ELISA, FuncS
    • Related Disease
    • Cancer

    Applications

    • Application Notes
    • This antibody has been tested for use in Enzyme-Linked Immunosorbent Assay and Functional Assay.

    Target

    • Alternative Names
    • C16orf54; Transmembrane protein C16orf54

    Product Notes

    This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

    • Increased sensitivity
    • Confirmed specificity
    • High repeatability
    • Excellent batch-to-batch consistency
    • Sustainable supply
    • Animal-free production

    See more details about Hi-Affi™ recombinant antibody benefits.

    Downloads

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    Select a product category from the dropdown menu below to view related products.
    Please select product type
    Mouse Antibody Products Extracellular Vesicle (EV) Antibody Products
    CAT Product Name Application Type
    TAB-1321CL-S(P) Anti-Human C16orf54 Recombinant Antibody scFv Fragment (R29-7-2A) ELISA
    TAB-1322CL-S(P) Anti-Human C16orf54 Recombinant Antibody scFv Fragment (R29-7-1 C) ELISA, FuncS
    TAB-1323CL-S(P) Anti-Human C16orf54 Recombinant Antibody scFv Fragment (R29-67-7A) ELISA, FuncS
    TAB-1324CL-S(P) Anti-Human C16orf54 Recombinant Antibody scFv Fragment (R29-67-4A) ELISA, FuncS
    TAB-1325CL-S(P) Anti-Human C16orf54 Recombinant Antibody scFv Fragment (R29-67-1 B) ELISA

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