Anti-CA6 (3ee9)-mc-vc-MMAE ADC (BAY-79-4620) (CAT#: ADC-L008)

This ADC product is composed of an anti-CA6 antibody (clone 3ee9) conjuagated via a Mc-vc linker to MMAE (3ee9-mc-vc-MMAE). It has demonstrated a response in lymphoma treatment by a MOA (Mechanism of Action) of Depolymerize Microtubules.

Specific Inquiry
  • Gene Expression
  • Datasheet
  • MSDS
  • COA
Normal Tissue
RNA Expression


  • Antibody Overview
  • Fully human IgG1 monoclonal antibody that binds to CA6
  • Clone
  • 3ee9
  • Antibody Conjugation
  • Human
  • Linker
  • mc-vc (maleimidocaproyl-valine-alanine)
  • Linker Class/Description
  • Peptide linkers, belonging to Enzymatically cleavable linkers, combine greater systemic stability with rapid enzymatic release of the drug in the target cell. The scission of peptidic bonds relies on lysosomal proteolytic enzymes, which have very low activities in blood due to endogenous inhibitors and the unfavorably high pH value of blood.
  • Drug
  • MMAE (Monomethyl auristatin E)
  • Drug Class/Description
  • Auristatins are water-soluble dolastatin analogs of dolastatin 10. Dolastatin 10 belongs to dolastatin family and it can powerfully bind to tubulin, thus inhibiting polymerization mediated through the binding to the vinca alkaloid binding domain, and causes cell to accumulate in metaphase arrest.


  • Introduction
  • The protein encoded by this gene is one of several isozymes of carbonic anhydrase. This protein is found only in salivary glands and saliva and protein may play a role in the reversible hydratation of carbon dioxide though its function in saliva is unknown.
  • Alternative Names


Download resources about recombinant antibody development and antibody engineering to boost your research.

See other products for "CA6"

Recombinant Antibody

CAT Product Name Application Type
MOB-145 Recombinant Anti-human CA6 Antibody WB, FC, FuncS IgG
MHH-145 Recombinant Human Anti-human CA6 Antibody ELISA, WB, IF, FuncS IgG

Fab Fragment Antibody

CAT Product Name Application Type
MOB-145-F(E) Recombinant Anti-human CA6 Antibody Fab Fragment ELISA, Nert, FuncS Fab
MHH-145-F(E) Recombinant Human Anti-human CA6 Antibody Fab Fragment ELISA, WB, IF, FuncS Fab

scFv Fragment Antibody

CAT Product Name Application Type
MOB-145-S(P) Recombinant Anti-human CA6 Antibody scFv Fragment ELISA, WB, IP, FuncS scFv
MHH-145-S(P) Recombinant Human Anti-human CA6 Antibody scFv Fragment IP, IF, Biosensors, FuncS scFv

Customer Reviews and Q&As

Submit a review or a question
There are currently no Customer reviews or questions for ADC-L008. Click the button above to contact us or submit your feedback about this product.
View the frequently asked questions answered by Creative Biolabs Support.

For Research Use Only. Not For Clinical Use.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

Send Inquiry

This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.

© 2024 Creative Biolabs.
  • 0
  • 0

    Go to compare