Hi-Affi™ Rabbit Anti-CAMK2B Recombinant Antibody (clone DS448AB)
CAT#: MOR-0448
Recombinant Rabbit anti-CAMK2B monoclonal antibody for WB, IHC, ICC, FC, excellent for producing superior results. Hi-Affi™ antibodies are developed from different sources, such as B cells of immunized animals, hybridoma, phage display library. The application of recombinant technology avoids the traditional ascitic fluid approach, which achieves the antibody generation in a humane way with much larger scale, greater specificity and sensitivity, and not susceptible to cell-line drift or lot-to-lot variation.
Gene Expression
Normal Tissue
Figure 1 High expression in cerebral cortex
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/26307/57641_B_7_5_val_selected.jpg
Normal Tissue
Figure 2 Low expression in pancreas
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/26307/57641_A_1_3_val_selected.jpg
Normal Tissue
Figure 3 IHC staining of human cerebral cortex
Immunohistochemical staining of human cerebral cortex shows strong nuclear and cytoplasmic positivity in neuronal cells.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/6849/ihc_selected.jpg
Normal Tissue
Figure 4 Cerebral cortex
Neuronal cells Staining: High Intensity: Strong Quantity: 75%-25% Location: Cytoplasmic/ membranous Neuropil Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/26307/57641_B_7_5.jpg
Normal Tissue
Figure 5 Cerebellum
Bergmann glia - cytoplasm/membrane Staining: Not detected Intensity: Negative Bergmann glia - nucleus Staining: Not detected Intensity: Negative GLUC cells - cytoplasm/membrane Staining: Not detected Intensity: Negative GLUC cells - nucleus Staining: Not detected Intensity: Negative Granular cells - cytoplasm/membrane Staining: Medium Intensity: Moderate Granular cells - nucleus Staining: Not detected Intensity: Negative Molecular layer - neuropil Staining: Medium Intensity: Moderate Molecular layer cells - cytoplasm/membrane Staining: Not detected Intensity: Negative Molecular layer cells - nucleus Staining: Not detected Intensity: Negative Processes in granular layer Staining: Not detected Intensity: Negative Processes in molecular layer Staining: Not detected Intensity: Negative Processes in white matter Staining: Medium Intensity: Moderate Purkinje cells - cytoplasm/membrane Staining: High Intensity: Strong Purkinje cells - dendrites Staining: High Intensity: Strong Purkinje cells - nucleus Staining: Not detected Intensity: Negative Synaptic glomeruli - capsule Staining: Not detected Intensity: Negative Synaptic glomeruli - core Staining: High Intensity: Strong White matter cells - cytoplasm/membrane Staining: Medium Intensity: Moderate White matter cells - nucleus Staining: High Intensity: Strong
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/26307/57641_B_7_8.jpg
RNA Expression
Figure 6 RNA cell line category: Cell line enriched (SCLC-21H)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000058404-CAMK2B
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Specifications
- Host Species
- Rabbit
- Derivation
- Phage display library screening
- Type
- Rabbit IgG
- Species Reactivity
- Human
- Clone
- DS448AB
- Applications
- WB, IHC, ICC, FC
- Conjugate
- Unconjugated
Product Property
- Purification
- Purified with Absolute Mag™ Protein A Agarose
- Purity
- >95% as determined by analysis by SDS-PAGE
- Format
- Liquid
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Target
- Alternative Names
- Calcium/Calmodulin-Dependent Protein Kinase II Beta; Proline Rich Calmodulin-Dependent Protein Kinase; CaM Kinase II Beta Subunit; CaM-Kinase II Beta Chain; CaMK-II Subunit Beta; EC 2.7.11.17; CAMKB; CAMK2; CAM2; Calcium/Calmodulin-Dependent Protein Kinase (CaM Kinase) II Beta; Calcium/Calmodulin-Dependent Protein Kinase Type II Beta Chain; CaM Kinase II Subunit Beta; EC 2.7.11
- Gene ID
- 816
- UniProt ID
- Q13554
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Related Signaling Pathways
cAMP Signaling Pathway
Canonical Wnt Signaling Pathway
ErbB Signaling Pathway
Non-Canonical Wnt Signaling Pathway
Related Diseases
Amphetamine Addiction
Cushing Syndrome
Downloadable Resources
Download resources about recombinant antibody development and antibody engineering to boost your research.
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
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Protocol & Troubleshooting
We have outlined the assay protocols, covering reagents, solutions, procedures, and troubleshooting tips for common issues in order to better assist clients in conducting experiments with our products. View the full list of Protocol & Troubleshooting.
See other products for "CAMK2B"
Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-3806z | Mouse Anti-CAMK2B Recombinant Antibody (clone 36D12) | ELISA, IHC, WB | Mouse IgG1, κ |
| MOB-0299CT | Mouse Anti-CAMK2B Recombinant Antibody (clone EML271) | IHC-P, WB | Mouse IgG1 |
| VS3-WK1387 | Mouse Anti-CAMK2B Recombinant Antibody (VS3-WK1387) | IHC-p | Mouse IgG |
| VS3-FY183 | Recombinant Rabbit Anti-CAMK2B Antibody (clone R05-9G5) | WB | Rabbit IgG |
| VS3-FY2642 | Mouse Anti-CAMK2B Recombinant Antibody (VS3-FY2642) | WB, IHC | Mouse IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-XY953 | Anti-CAMK2B Immunohistochemistry Kit | IHC | |
| VS-0525-XY954 | Anti-Mouse CAMK2B Immunohistochemistry Kit | IHC |
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