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    Mouse Anti-CASP1 Recombinant Antibody (clone 12G12) (CAT#: MOB-3801z)

    This product is a mouse antibody that recognizes human CASP1. It can be used in the following applications: WB, IF, IHC, IP.

    Specific Inquiry
    • Size:

    • Conjugation:

    • Endotoxin:

    • Purity:

    • Formats:

    • Isotype Switching:

    • Fc Engineering:

    • Modalities:

    Custom Production

    We specialize in custom recombinant antibody production, offering seamless execution from provided sequences to high-quality antibody deliverables, ensuring optimal yield and purity.

    Sequences:
    Isotype :
    Purity :
    Endotoxin :
    Quantity :
    Conjugation :
    Fc Engineering :
    Modalities :
    Other Requirements:
    We require custom production
    • Gene Expression
    • Datasheet
    • MSDS
    • COA
    Subcellular Location and Protein Expression
    Figure 1 IF staining of human cell line U-251 MG
    Figure 1 IF staining of human cell line U-251 MG
    (Immunofluorescent staining of human cell line U-251 MG shows localization to cytosol.)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/2685/634_E8_2_selected.jpg
    Figure 2 IHC staining of human urinary bladder
    Figure 2 IHC staining of human urinary bladder
    (Immunohistochemical staining of human urinary bladder shows strong nuclear and cytoplasmic positivity in urothelial cells.)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/3056/ihc_selected.jpg
    Figure 3 IHC staining of human small intestine
    Figure 3 IHC staining of human small intestine
    (Immunohistochemical staining of human small intestine shows strong cytoplasmic positivity in glandular cells.)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/2685/ihc_selected.jpg
    Figure 4 IF staining of human cell line A-431
    Figure 4 IF staining of human cell line A-431
    (Immunofluorescent staining of human cell line A-431 shows localization to cytosol.)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/2685/639_E8_1_blue_red_green.jpg
    Figure 5 IF staining of human cell line U-2 OS
    Figure 5 IF staining of human cell line U-2 OS
    (Immunofluorescent staining of human cell line U-2 OS shows localization to cytosol.)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/2685/635_E8_3_blue_red_green.jpg
    Normal Tissue
    Figure 6 Colon
    Figure 6 Colon
    (Peripheral nerve/ganglion
    Staining:Medium
    Intensity: Moderate
    Quantity:>75%
    Location: Cytoplasmic/membranous)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/2685/6753_A_7_3.jpg
    Figure 7 Testis
    Figure 7 Testis
    (Round or early spermatids
    Staining:Medium
    Intensity: Moderate
    Quantity:>75%)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/2685/6753_A_4_6.jpg
    RNA Expression
    Figure 8 RNA cell line category: Cell line enhanced (BJ hTERT+, HBEC3-KT, HHSteC, U-937)
    Figure 8 RNA cell line category: Cell line enhanced (BJ hTERT+, HBEC3-KT, HHSteC, U-937)
    (Cell lines ordered by descending RNA expression order.)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000137752-CASP1

    Specifications

    • Immunogen
    • Human Caspase 1, Apoptosis-Related Cysteine Peptidase
    • Host Species
    • Mouse
    • Derivation
    • Mouse
    • Type
    • Mouse IgG1, κ
    • Specificity
    • Human CASP1
    • Species Reactivity
    • Human
    • Clone
    • 12G12
    • Applications
    • WB, IF, IHC, IP

    Product Property

    • Purity
    • >95% as determined by SDS-PAGE
    • Concentration
    • Please refer to the vial label for the specific concentration.
    • Storage
    • Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

    Applications

    • Application Notes
    • This antibody has been reported for use in Western Blot, Immunofluorescence Assay, Immunohistochemistry Assay, Immunoprecipitation Assay.

    Target

    • Alternative Names
    • CASP1; P45; IL-1 Beta-Converting Enzyme; Caspase 1, Apoptosis-Related Cysteine Peptidase; Interleukin-1 Beta Convertase; CASP1 Nirs Variant 1; IL1BC; Convertase; CASP-1; IL1BCE; EC 3.4.22.36; Caspase 1, Apoptosis-Related Cysteine Peptidase (Interleukin 1,

    Related Resources

    • Related Signaling Pathways

    Product Notes

    This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

    • Increased sensitivity
    • Confirmed specificity
    • High repeatability
    • Excellent batch-to-batch consistency
    • Sustainable supply
    • Animal-free production

    See more details about Hi-Affi™ recombinant antibody benefits.

    Downloads

    Download resources about recombinant antibody development and antibody engineering to boost your research.

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    For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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