Recombinant Anti-human CASP7 Intrabody [(D-Arg)9]
CAT#: IAB-B072(A)
Recombinant anti-CASP7 intrabody linked to (D-Arg)9 works within cells to bind human CASP7, expressed in CHO cells.
Gene Expression
Normal Tissue
Figure 1 Small intestine
Glandular cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/25563/59600_A_4_2.jpg
Normal Tissue
Figure 2 Colon
Endothelial cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous Glandular cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/25563/59600_A_7_3.jpg
Normal Tissue
Figure 3 Kidney
Cells in tubules Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/25563/59600_A_9_5.jpg
Normal Tissue
Figure 4 Testis
Spermatogonia cells Staining: Medium Intensity: Moderate
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/25563/59600_A_4_6.jpg
Normal Tissue
Figure 5 Lymph node
Germinal center cells Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous Non-germinal center cells Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/25563/59600_A_9_8.jpg
RNA Expression
Figure 6 RNA cell line category: Low cell line specificity
Cell lines ordered by descending RNA expression order
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000165806-CASP7
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Specifications
- Immunogen
- human caspase 7, apoptosis-related cysteine peptidase
- Host Species
- human
- Type
- scFv-(D-Arg)9
- Cell Penetrating Peptide
- (D-Arg)9
It has been proven that polyarginine peptides composed of nine arginine amino acids (Arg-9) are able to translocate across cells very efficiently. This raises the question if molecular dynamics simulations would show a similar pathway for this highly hydrophilic and charged peptide as predicted for the Tat peptide. The simplicity of Arg-9 over other CPPs also helps isolate the role of the Arg sidechain on the translocation without the effect of other sidechains. Therefore, in this work we study computationally the translocation of Arg-9 through a lipid bilayer and show that the translocation mechanism is the same as for the Tat peptide.
- Species Reactivity
- human
- Applications
- Products can be used for: Western blot; Immunocytochemistry; Functional studies
Product Property
- Purity
- >95%, by SDS-PAGE, under reducing conditions
- Storage
- 4°C or -20°C, avoid repeated freezing and thawing.
Target
- Alternative Names
- Apoptosis related cysteine peptidase; Apoptosis related cysteine protease; Apoptotic protease MCH 3; Apoptotic protease Mch-3; Apoptotic protease MCH3; CASP 7; CASP-7; CASP7; CASP7_HUMAN; Caspase 7; Caspase 7 apoptosis related cysteine peptidase; Caspase
- Gene ID
- 480
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Related Signaling Pathways
TNF Signaling Pathway
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Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
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COA
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|---|---|---|---|
| IAB-B072(G) | Recombinant Anti-human CASP7 Intrabody [+36 GFP] | WB, ICC, Neut, FuncS | scFv-(+36GFP) |
| IAB-B072(T) | Recombinant Anti-human CASP7 Intrabody [Tat] | IF, FC, FuncS | scFv-Tat |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-0478 | Hi-Affi™ Rabbit Anti-CASP7 Recombinant Antibody (clone DS478AB) | IF, IHC-P, IP, WB | Rabbit IgG |
| CAT | Product Name | Application | Type |
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0724-YC1356 | AbPlus™ Anti-CASP7 Magnetic Beads (VS-0724-YC1356) | IP, Protein Purification |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0325-XY320 | Anti-CASP7 Immunohistochemistry Kit | IHC | |
| VS-0525-XY1007 | Anti-Mouse CASP7 Immunohistochemistry Kit | IHC | |
| VS-0525-XY1006 | Anti-Human CASP7 Immunohistochemistry Kit | IHC | |
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